[Transglutaminase 6] Human neuronal transglutaminase [T021]_ZEDIRA - 코아사이언스

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Human neuronal transglutaminase

(TG6, recombinantly produced in insect cells)

Cat.# T021 / Size: 250ug, 1mg

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Documents

PDS MSDS

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Synonym

Neuronal Transglutaminase, TGy, TG6, TGase 6, protein-glutamine-γ-glutamyltransferase

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Molecular Weight

78 kDa

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Source

Recombinantly produced in insect cells

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Purity

> 95% [SDS-PAGE and Coomassie staining]

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Activation

His6-rhTG6 is a Ca2+-dependent enzyme.

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Appearance

White lyophilized solid.

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Reagents

The Transglutaminase is lyophilized from 10 mM Tris-HCl pH 8.2, 500 mM NaCl, 2 mM DTT. Sample contains sucrose.

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Reconstitution

Add the volume of water specified in the certificate of analysis under aliquotation to the vial of lyophilized powder. Rotate vial gently until solid dissolves. After reconstitution the solution should be stored frozen in working aliquots. For short term storage keep cooled on ice.

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Application

His6-rhTG6 catalyzes acyl transfer reactions from glutamine residues in proteins or peptides to primary amines, e. g. the formation of ε-(γ-glutamyl) lysine bonds between proteins by transferring the acyl group of a peptide-bound glutamine residue to the primary amino group of a peptide-bound lysine residue.

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Storage

T021 is stable for at least one year if stored at ≤ -20°C.

Avoid freeze-thaw cycles.

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Reference(s)

Fukui et al., FEBS J. 2013, 280:1420-9

Schaertl et al., J. Biomol. Screen. 2010, 15:478-87

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Note

Intended for research use only, not for use in human, therapeutic or diagnostic applications.

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Related Products

T064: Inhibited human neuronal transglutaminase

A031: FITC-labeled polyclonal antibody to human TG6

T036: Transglutaminase Assay Kit ("DCC"), fluorescent

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