Cytokine Related products_ELK Biotechnology - 코아사이언스

Introduction

Cytokine (CK) is a type of small molecule protein with a wide range of biological activities. It is composed of immune cells (such as monocytes, macrophages, T cells, B cells, NK cells, etc.) and some non-immune cells. (Endothelial cells, epidermal cells, fibroblasts, etc.) are synthesized and secreted upon stimulation. Cytokines bind to their target cells through receptors on the cell surface and exert their effects through signal transduction pathways. Their modes of action in the body are roughly divided into three types: autocrine, paracrine and endocrine. They have the function of regulating innate immunity and acquired immunity, Repair damaged tissue, mediate inflammatory response, pluripotent stem cells (APSC pluripotent cells), cell growth, blood cell production, and other functions.

 

Cytokine production and classification
 
Depending on the source, cytokines can be divided into:
 
1) Lymphokine is produced by lymphocytes (B lymphocytes, T lymphocytes and NK cells), such as IL-2, IFN-γ, GM-CSF and neuroleukin, etc.
2) Monokine, produced by monocytes or macrophages, such as IL-1, TNF-α, G-CSF and M-CSF, etc. 
3) Cytokines produced by macrophages are produced by vascular endothelial cells, stromal cells and other cells in the bone marrow and thymus, such as IL-7, SCF, IFN-β, etc.
 
According to their functions, cytokines can be divided into:
1) Interleukin (IL), a cytokine produced by monocytes, lymphocytes or other non-monocytes, plays an important regulatory role in immune regulation, cell-cell interaction, hematopoiesis and inflammatory processes.
2) Interferon (IFN), according to the structure and source of interferon production, can be divided into IFN-α produced by leukocytes, IFN-β produced by fibroblasts and IFN-γ produced by activated T cells.
3) Tumor necrosis factor (TNF), which can cause necrosis of tumor tissue. According to its production source and structure, it can be divided into TNF-α produced by monocytes and macrophages and TNF-α produced by activated T cells. Two types of TNF-β.
4) Colony stimulating factor (CSF). CSF can not only stimulate the differentiation of hematopoietic stem cells at different stages of development, but also promote the function of mature cells. According to the different cell colonies formed, they are mainly divided into G (granulocyte)-CSF, M (macrophage)-CSF, GM (granulocyte, macrophage)-CSF, Multi (multiple)-CSF (IL-3 ), SCF, EPO, etc.
5) Transforming growth factor-β family (TGF-β family), including the following (TGF-β1, TGF-β2, TGF-β3, TGFβ1β2, etc.).
6) Growth factors (GF), including epidermal growth factor (EGF), fibroblast growth factor (FGF), oncostatin M (OSM), IGF-Ⅱ, leukemia inhibitory factor (LIF), nerve growth factor (NGF) etc.
7) Chemokine family, including C-X-C/α subfamily, C-C/β subfamily, C-type subfamily, CX3C subfamily, etc.

 

 

ELK Related products
 
ELK1396 Rat TNFa(Tumor Necrosis Factor Alpha) ELISA Kit
IF:19.227
https://doi.org/10.1016/j.bbi.2022.02.015
IF:9.587
https://doi.org/10.1186/s12974-021-02294-w
IF:9.43
https://doi.org/10.1186/s12951-023-01790-w
IF:8.786
https://doi.org/10.3389/fimmu.2022.913901
 
ELK1387 Mouse TNFa(Tumor Necrosis Factor Alpha) ELISA Kit
IF:17.4
https://doi.org/10.1016/j.nantod.2023.102009 
IF10.6
https://doi.org/10.1002/ctm2.1546
IF:8.2
https://doi..org/10.1016/j.ijbiomac.2024.131520
IF:8.2
https://doi.org/10.1016/j.ijbiomac.2023.129074
 
ELK1395 Mouse TNFa(Tumor Necrosis Factor Alpha) ELISA Kit
IF:15.135
https://doi.org/10.1002/smll.202107838
IF:6.073
https://doi.org/10.3389/fcimb.2022.1068324
IF:5.988
https://doi.org/10.3389/fphar.2021.781856
IF:5.753
https://doi.org/10.1111/hel.12785
 
ELK1190 Human TNFa(Tumor Necrosis Factor Alpha) ELISA Kit
IF:12.771
https://doi.org/10.1186/s12929-021-00711-z
IF:8.3
https://doi.org/10.1016/j.envres.2023.116970
IF:7.5
https://doi.org/10.1016/j.biopha.2023.116027
IF:6.529
https://doi.org/10.1016/j.biopha.2021.112071
 
ELK1270 Human IL1b(Interleukin 1 Beta) ELISA Kit
IF:12.771
https://doi.org/10.1186/s12929-021-00711-z
IF: 8.3
https://doi.org/10.1016/j.envres.2023.116970
IF:6.529
https://doi.org/10.1016/j.biopha.2021.112071
IF:6.011
https://doi.org/10.1093/jleuko/qiad054
 
ELK1272 Rat IL1b(Interleukin 1 Beta) ELISA Kit
IF:19.227
https://doi.org/10.1016/j.bbi.2022.02.015
IF:15.863
https://doi.org/10.1186/s40824-023-00339-0
IF:9.587
https://doi.org/10.1186/s12974-021-02294-w
IF:8.786
https://doi.org/10.3389/fimmu.2022.913901
 
ELK1271 Mouse IL1b(Interleukin 1 Beta) ELISA Kit
IF:15.153
https://doi.org/10.1002/smll.202107838
IF:10.6
https://doi.org/10.1002/ctm2.1546
IF:8.2
https://doi.org/10.1016/j.ijbiomac.2024.131520
IF:7.5
https://doi.org/10.1016/j.biopha.2023.116027
 
ELK1158 Rat IL6(Interleukin 6) ELISA Kit
IF:19.227
https://doi.org/10.1016/j.bbi.2022.02.015
IF:18.9
https://doi.org/10.1016/j.bioactmat.2023.03.011
IF:15.863
https://doi.org/10.1186/s40824-023-00339-0
IF:9.578
https://doi.org/10.1186/s12974-021-02294-w
 
ELK1157 Mouse IL6(Interleukin 6) ELISA Kit
IF:11.153
https://doi.org/10.1002/smll.202107838
IF:10.6
https://doi.org/10.1002/ctm2.1546
IF:8.2
https://doi.org/10.1016/j.ijbiomac.2023.129074
IF:7.5
https://doi.org/10.1016/j.biopha.2023.116027
 
ELK1156 Human IL6(Interleukin 6) ELISA Kit
IF:7.31
https://doi.org/10.1155/2022/2405972
IF:6.543
https://doi.org/10.1155/2020/7106525
IF:6.529
https://doi.org/10.1016/j.biopha.2021..112071
IF:6.1
https://doi.org/10.1016/j.bcp.2022.115343
 
ELK1142 Human IL10(Interleukin 10) ELISA Kit
IF:6.011
https://doi.org/10.1093/jleuko/qiad054
IF:5.714
https://doi.org/10.1016/j.intimp.2022.109473
IF:5.004
https://doi.org/10.1002/ddr.22000
IF:5.5
https://doi.org/10.1093/jleuko/qiad054
 
ELK1143 Mouse IL10(Interleukin 10) ELISA Kit
IF:10.6
https://doi.org/10.1002/ctm2.1546
IF:8.2
https://doi.org/10.1016/j.ijbiomac.2024.131520
IF:6.261
https://doi.org/10.21203/rs.3..rs-109643/v1
IF:6.064
https://doi.org/10.3389/fmicb.2022.820838
 
ELK1144Rat IL10(Interleukin 10) ELISA Kit
IF:9.43
https://doi.org/10.1186/s12951-023-01790-w
IF:7.419
https://doi.org/10.1016/j.biopha.2020.110912
IF:5.6
https://doi.org/10.1016/j.intimp.2023.111369
IF:4.379
https://doi.org/10.1038/s41598-019-56535-3

코아사이언스 coresciences Korea ELK Biotechnology CO.,LTD ELK (Wuhan) Biotechnology CO.,Ltd. 한국 대리점 ELISA antibody 항체 면역학 연구 세포배양 분자생물학 시약