[Functional Coatings] NEXTERION® Aldehydesilane Coating (AL)_Schott Nexterion/SCHOTT MINIFAB - 코아사이언스

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Microarray용 glass slide 전문 브랜드 Schott Nexterion 한국 대리점 코아사이언스 입니다.

다양한 functional group으로 코팅된 고품질의 coating slide glass를 공급하고 있습니다.

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NEXTERION® Aldehydesilane Coating (AL)

 

The NEXTERION® AL coating represents a uniform surface featuring aldehyde groups, that are readily reactive to primary amines in order to bind all types of amino-containing or amino-modified bio-molecules.  

 

The covalent bond formed at the terminus of the nucleic acid offers both: stability and maximal base pairing opportunity. The covalent binding diminishes sample loss during the course of experiments and permits stringent washing steps, which reduce background noise and allow greater sensitivity. Additional immobilization steps, such as baking or UV cross-linking, are not required for immobilization.  

 

Produced in ISO class 5 clean room conditions using a standardized process and running a stringent quality control system, aldehydesilane coated substrates are available in standard and custom formats.

 

Product Information 

• Coating Chemistry

• Shelf Life
  Nine months for sealed packages at room temperature.

 

• Immobilization Method
  Covalent binding via amine reactive chemistry.
  
   
• Probe Types
  • Amino-modified PCR products and BACs/YACs
  • Amino-modified oligonucleotides
  • Small protein fragments such as peptides

 

Advantages 

• Material:
  • High-quality borosilicate glass
  • Alternative substrate materials can be offered
    
    
• Formats:
  • Standard sizes (slide format, SBS plate format)
  • Customized dimensions and thicknesses
    
    
• Structuring:
  • Pre-scoring
  • Hydrophobic coating for multiplexing
    
    
• Markings:
  • Barcodes (1D e.g. code 39, code 128; 2D e.g. QR, data matrix)
  • Logos
  • Position markings and fiducials
    
    
• Quality:
  • Excellent intra- and inter-lot reproducibility
  • Physical and functional quality control
  • ISO class 5 clean room production
  • Relevant processes in place for diagnostic company needs

Supply Forms 

Product	Size (mm)	Thickness (mm)	Pieces per pack
Slide AL	75.6 × 25.0	1.0	25
Plate AL	110.0 × 74.0	1.0	5
Customized AL	Variable	0.1–2.5	Variable

 

Downloads 

• MSDS >
• Brochure >
• Protocol >

 

Coating Selection Table 

SCHOTT MINIFAB offers a wide range of functional coating chemistries for DNA and protein microarrays as well as other applications.  

 

The following table indicates the most appropriate coating for specific applications.

 

Probe type	Nexterion Coating
Oligonucleotides	Aminosilane, Epoxysilane, 3-D Hydrogel, 3-D Polymer
cDNA/PCR	Aminosilane, Epoxysilane, Aldehydesilane
Bacterial artificial chromosomes (BAC)	Aminosilane, Epoxysilane, Aldehydesilane
Peptides	Epoxysilane, Aldehydesilane
Proteins	3-D Hydrogel, 3-D Polymer
Antibodies	Epoxysilane, Aldehydesilane, 3-D Hydrogel, 3-D Polymer
Glycans	3-D Hydrogel, 3-D Polymer
Cells/tissues	Depending on type of cell/tissue, please contact us for support and free-of-charge evaluation samples
Biotin modified molecules	Streptavidin

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