[Functional Coatings] NEXTERION® Streptavidin Coating (HS)_Schott Nexterion/SCHOTT MINIFAB - 코아사이언스

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Microarray용 glass slide 전문 브랜드 Schott Nexterion 한국 대리점 코아사이언스 입니다.

다양한 functional group으로 코팅된 고품질의 coating slide glass를 공급하고 있습니다.

관련 문의는 전화 02-858-0328 또는 info@coresciences.co.kr로 주세요~

 

NEXTERION® Streptavidin Coating (HS)

 

The NEXTERION® Streptavidin coating is specifically developed for binding all types of biotinylated molecules. Biotin-tagged molecules are immobilized in a directional way to the streptavidin molecules and applied onto the glass substrate.  

 

The proprietary thin-film deposition coating process produces a very high density, as well as an extremely uniform coating of streptavidin molecules. The resulting surface has a very high binding capacity combined with a low signal variance across a single slide as well as different slides and batches.  

 

Produced in ISO class 5 clean room conditions using a standardized process and running a stringent quality control system, streptavidin coated substrates are available in standard and custom formats.

 

Product Information 

• Coating Chemistry

• Shelf Life
  Six months for sealed packages when stored at –20°C.
  To protect the activity of the streptavidin layer, a protective coating is added on top of the reactive coating prior to packaging. This layer must be removed prior to use by a washing step. The streptavidin layer on Slide HS is very sensitive to elevated temperatures. It is therefore necessary to ship the product in a frozen state with dry ice. The product must immediately be put into a freezer upon arrival. Repeated freeze and thaw cycles should be avoided.
   
• Immobilization Method
  Binding via biotin.
   
• Probe Types
  • All molecules that can be biotinylated

 

Advantages 

• Material:
  • High-quality borosilicate glass
  • Alternative substrate materials can be offered
    
    
• Formats:
  • Standard formats (slide, SBS plate)
  • Customized dimensions and thicknesses
  • Pre-scoring options
    
    
• Features:
  • Barcodes (1D, 2D, QR, data matrix)
  • Logos
  • Position markings and fiducials
  • Hydrophobic coating for multiplexing
    
    
• Quality:
  • Excellent intra- and inter-lot reproducibility
  • Physical and functional quality control
  • ISO class 5 clean room production
  • Relevant ISO 13485 processes in place for diagnostic company needs

 

Downloads 

• Brochure >
• Protocol >

 

Coating Selection Table 

SCHOTT MINIFAB offers a wide range of functional coating chemistries for DNA and protein microarrays as well as other applications.  

 

The following table indicates the most appropriate coating for specific applications.

 

Probe type	Nexterion Coating
Oligonucleotides	Aminosilane, Epoxysilane, 3-D Hydrogel, 3-D Polymer
cDNA/PCR	Aminosilane, Epoxysilane, Aldehydesilane
Bacterial artificial chromosomes (BAC)	Aminosilane, Epoxysilane, Aldehydesilane
Peptides	Epoxysilane, Aldehydesilane
Proteins	3-D Hydrogel, 3-D Polymer
Antibodies	Epoxysilane, Aldehydesilane, 3-D Hydrogel, 3-D Polymer
Glycans	3-D Hydrogel, 3-D Polymer
Cells/tissues	Depending on type of cell/tissue, please contact us for support and free-of-charge evaluation samples
Biotin modified molecules	Streptavidin

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