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MC-Val-Cit-PAB-SN38

Cat.# BP-40210 / Size: 1mg, 5mg

MC-Val-Cit-PAB-SN38 is a cleavable ADC linker featuring a maleimide, a Val-Cit dipeptide, a PAB group and an SN38 warhead. Maleimide is a covalent ligand used for linking thiols such as those in cysteines residues in proteins, while the Val-Cit-PAB motif is an enzyme-cleavable linker. This linker efficiently releases the toxin, SN38, to target cells to cause cellular apoptosis.

Formula: C51H58N8O13
MW: 991.1
CAS: 1801838-28-7
Purity: 98%
 
Storage Condition: -20°C
Shipping: Ambient temperature
Availability: In Stock
NMR: View

 

* 본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

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