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Bile Acid Metabolite Library of Standards

Cat.# BACSMLS

 

Bile Acid/Carnitine/Sterol Metabolite Library of Standards (BACSMLS) is a collection of high-quality bile acids, carnitines and sterols. Metabolite libraries make it simple to locate hundreds of metabolites in metabolomics analysis, most commonly used in metabolite qualification and quantification for MS and phenotypic screening.

Bile acids are biologically important small molecules that the liver produces bile acids and they are found predominantly in the bile of mammals and other vertebrates. About 80% of the organic compounds in bile are bile acids and the remainder is made up of phospholipids and cholesterol. Bile acids are conjugated with taurine or glycine residues to give anions called bile salts. Once secreted into the lumen of the intestine, bile salts are modified by gut bacteria. The gut bacteria partially dehydroxylates the bile acids and removes and their glycine and taurine groups to produce secondary bile acids.

Bile acids regulate various metabolic processes including triglyceride, cholesterol, glucose and energy homeostasis. Bile acids also have hormonal actions throughout the body, aid in the mobility and reduction of bacterial flora found in the small intestine and biliary tract. The disruption of processes in involved in the metabolism or circulation of bile acids has been linked to disorders of the intestine such as colon cancer and inflammatory bowel disease. Because of the importance of bile acids especially in the maintenance of microbiota health, bile acids are receiving a great deal of attention.

This metabolite library contains 96 bile acids, carnitines and sterols. Please contact us for an up-to-date list.

For additional metabolite libraries, please be sure to check out our comprehensive library list.

Bile Acid Metabolite Library

The Bile Acid metabolite Library Kit Contents: Plate Map, User Manual, MLSDiscovery software tool

  • CONVENIENT 96-WELL FORMAT Easy storage, no glass bottles; plated to allow row multiplexing for efficient processing
  • HIGH PURITY and STABLE 5 µg dried weight/compound; plenty of material for multiple injections
  • MLSDiscovery™ SOFTWARE Data processing, collection and reduction tool creates libraries in hours

Preparation Instructions Use compounds as standards and inject individually, or employ a strategy to pool compounds to allow multiple mixtures to be analyzed per injection. For more information, please refer to the Product Sheet.

Storage/Stability Store at –20 °C, long-term at –80 °C; protect from moisture and light. Avoid freeze/thaw cycles.

Precautions and Disclaimer The BACSMLS product is for laboratory research use only. Wear safety glass and handle with gloves. Avoid contact with skin and eyes.

Legal Information BACSMLS is a trademark of IROA Technologies LLC.

*본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

코아사이언스 coresciences IROA Technologies LCC Korea 한국 메타볼로믹스 대사체학 연구 시약 내부 표준물질 metabolomics research Internal Standards for Metabolomics Libraries for Mass Spectometry 대사 프로파일링 도구 metabolite normalization 대사체 정규화 ion suppression eagents Cell Proliferation Kits 올리고핵산 올리고뉴클레오티드 표지