[Newsletter] 2024년 11월 New Compounds_TargetMol - 코아사이언스

2024년 11월 New Compounds from TargetMol

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TargetMol (Target molecule Corp.) 공식 수입/공급 업체 코아사이언스 입니다.

 

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Inhibitors & Agonists Compound Libraries Recombinant Proteins Virtual Screening

 

ZD-6888 Hydrochloride

ZD-6888 Hydrochloride (ZD-6888 HCl) is an angiotensin II (AII) antagonist that mediates AII receptor blockade and induces a competitive inhibition of AII-mediated renin release.

Research Areas: Neurological Disease
Targets: Dopamine Receptor

 

PAOPA

PAOPA is a novel dopamine D2 receptor modulator and L-proline-L-leucine-glycine amide (PLG) peptide mimetic that prevents and reverses behavioral and biochemical abnormalities in preclinical animal models of schizophrenia sensitized to amphetamine. PAOPA has been used in the study of schizophrenia and extrapyramidal dysfunction.

Research Areas: Tuberculosis
Targets: Others

 

5-OP-RU

5-OP-RU is a MAIT-activating ligand, the major antigen of MAIT cells, a mucosal adjuvant, induces efficient enrichment of mucosal-associated invariant T cells, and can be used to study Mycobacterium tuberculosis infections.

Research Areas: Infection

Targets: Others

 

BI-4732

BI-4732 is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with high blood-brain barrier permeability, antitumor activity, inhibition of EGFR activation, and inhibition of T790M mutations.

Research Areas: Cancer
Targets: EGFR

 

Cianopramine

Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.

Research Areas: Neurological Disease
Targets: 5-HT Receptor

 

Leritrelvir

Leritrelvir (RAY1216) is an orally active and highly potent protease inhibitor with antiviral activity that blocks cleavage of viral precursor proteins and inhibits viral replication in SARS-CoV-2.

Research Areas: Infection
Targets: SARS-CoV

 

Valomaciclovir stearate

Valomaciclovir stearate (A-174606. 0) is a nucleoside analog with antiviral activity against varicella-zoster virus (VZV), and has been used in the study of VZV infections.

Research Areas: Infection
Targets: HSV  

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