Helper lipids supply for your LNP development_Biopharma PEG Scientific Inc. - 코아사이언스

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PEG 및 PEG derivatives 합성 전문 제조사 Biopharma PEG Scientific Inc. 한국 대리점 코아사이언스 입니다.

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Lipid Nanoparticles (LNPs) are delivery systems commonly employed in the field of nucleic acid drugs.  All the current FDA-approved LNP formulations contain four lipids: (1) an ionizable cationic lipid, helper lipids which include (2) phospholipid (3) cholesterol, and (4) a PEG-lipid conjugate.

 

Biopharma PEG can provide plant-derived cholesterol, DSPE and PEG Lipids for LNPs for commercial applications and clinical trials.

Cholesterol (Plant-Derived) CAS No. 57-88-5 Purity: 99% Plant-derived cholesterol can be used as helper lipids in LNP formulations as it enhances particle stability by regulating membrane integrity and rigidity.

DSPE CAS No. 1069-79-0 DSPE is a water soluble derivative of phosphatidylethanolamine with (18:0) stearic acid acyl chains. It is the staring material for the synthesis of mPEG-DSPE for the preparation of LNPs.

PEG Lipids

mPEG-DSPE M.W,  1K, 2K, 3.4K, 4K, 5K, 10K, 20K CAS No. 147867-65-0 A PEG-based phospholipid can be used in targeted drug delivery and drug solubility enhancement. DSPE-PEG-NH2 M.W.  1K, 2K, 3.4K, 5K, 6K, 8K, 10K, 20K CAS No. 474922-26-4 DSPE-PEG-Mannose M.W.  1K, 2K, 3.4K, 5K, 10K, 20K

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코아사이언스 coresciences Biochempeg Scientific Inc.USA Korea distributor 한국 대리점 Biochempeg,  founded in 2013,  is a biotechnology-oriented company in Watertown, Massachusetts. We are dedicated to manufacturing and supplying high purity polyethylene glycol (PEG) derivatives and linkers, monodisperse PEG, ADC PEG linkers, Click Chemistry reagents,  PEGylation services and custom PEG derivative synthesis to clients worldwide. These PEG linkers have been widely used in bioconjugation, antibody-drug conjugates (ADCs) therapeutic, drug delivery and diagnostics field Biopharma PEG