VGX-1027 [522453][CAS no. 6501-72-0]_MedKoo Biosciences - 코아사이언스

VGX-1027

Cat.# 522453 / Size: 100mg, 200mg, 500mg, 1g

Description: VGX-1027 is a small potent nitric oxide-donating compound with potent immunomodulatory properties. VGX-1027, in microarray analysis, modulates the expression of genes that involved in immune activation and the antigen processing and presentation in response to lipopolysaccharide (LPS) stimulation. VGX-1027 is a TLR4 inhibitor. VGX-1027 is a TLR4 and TLR2/6 signaling pathway modulator. In CD4+CD25− T cells, VGX-1027 inhibited cell proliferation induced by enterobacterial antigen.

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CAS#: 6501-72-0

Chemical Formula: C11H11NO3

Exact Mass: 205.07389

Molecular Weight: 205.21

Elemental Analysis: C, 64.38; H, 5.40; N, 6.83; O, 23.39

 

Synonym: VGX-1027; VGX 1027; VGX1027; GIT 27; GIT-27; GIT27

IUPAC/Chemical Name: 2-(3-phenyl-4,5-dihydroisoxazol-5-yl)acetic acid

InChi Key: MUFJHYRCIHHATF-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)

SMILES Code: O=C(O)CC1CC(C2=CC=CC=C2)=NO1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

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