[Small molecule inhibitors] SYNkinase 상품 소개 - 코아사이언스

안녕하세요!

Small molecule inhibitors 전문제조사 SYNkinase 수입/공급 업체 코아사이언스 입니다.

 

자세한 상품 정보 및 관련 문의는 전화 02-858-0328 또는 info@coresciences.co.kr로 문의주시기 바랍니다.

감사합니다!

 

Cat.#         Name [CAS no.]          Alt. Name  Formula  Kinase Group  Targets  Substrate Pathway
SYN-1001 ABT-737 [852808-04-9] ABT737 C42H45ClN6O5S2 PPI Bcl-2 N/A N/A
SYN-1002 Linifanib [796967-16-3] ABT-869, AL-39324, RG3635 C21H18FN5O RTK PDGFR Tyrosine Epigenetic
SYN-1003 Quizartinib [950769-58-1] AC220 C29H32N6O4S RTK PDGFR Tyrosine Epigenetic
SYN-1004 AG13958 [319460-94-1] AG13958 C26H22FN7O RTK VEGF Tyrosine N/A
SYN-1005 Akt-I-1 [473382-39-7] Akt-I-1,AktI1 C22H30N6 AGC AKT Serine-Threonine TGFb-SMAD - JAK-STAT - mTOR - BTK
SYN-1006 Akt-I-1,2 HCl [473382-50-2] Akt-I-1,2 HCl C23H21N3.HCl AGC AKT Serine-Threonine NF-kB - TGFb-SMAD - JAK-STAT - mTOR - BTK
SYN-1007 AMG-47a [882663-88-9] AMG47a C29H28F3N5O2 TKL LIMK Serine-Threonine N/A
SYN-1008 AMG-Tie2-1 [870223-96-4] AMG-Tie2-1 C25H20F3N5O2 RTK Tie-2 Tyrosine N/A
SYN-1009 AS-252424 [900515-16-4] AS252424 C14H8FNO4S Lipid Kinase PI3K Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1010 AT-7519 HCl [902135-91-5] AT-7519 HCl C16H17Cl2N5O2.HCl CMGC CDK2 - CDK7 - CDK5 - CDK4 Serine-Threonine Cell Cycle - Epigenetic 
SYN-1011 AT9283 [896466-04-9] AT9283 C19H23N7O2 Other Aurora A Serine-Threonine Cell Cycle
SYN-1012 AV-412 [451492-95-8] MP412, AV412, MP-412 C27H28ClFN6O RTK EGFR Tyrosine JAK-STAT - Epigenetic
SYN-1013 Tivozanib [ 475108-18-0] Tivozanib, AV-951 C22H19ClN4O5 RTK VEGFR Tyrosine N/A
SYN-1015 AZ-960 [905586-69-8] AZ960 C18H16F2N6 PTK JAK2 Tyrosine JAK-STAT
SYN-1016 Selumetinib [606143-52-6] AZD6244, ARRY142886 C17H15BrClFN4O3 Atypical (PIKK) mTOR Serine-Threonine TGFb-SMAD - JAK-STAT - mTOR
SYN-1017 AZD7762 HCl [1246094-78-9] AZD7762 HCl C17H19FN4O2S.HCl CAMK Chk1 Serine-Threonine Cell Cycle
SYN-1018 BEZ-235 [915019-65-7] NVP-BEZ235, BEZ235 C30H23N5O Atypical (PIKK) mTOR - PI3K Serine-Threonine NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1019 (R)-BI-2536 [755038-02-9] (R)-BI-2536 C28H39N7O3 Other Plk1 Serine-Threonine N/A
SYN-1020 BI-D1870 [501437-28-1] BID1870 C19H23F2N5O2 AGC S6K Serine-Threonine TGFb-SMAD - mTOR 
SYN-1021 Bisindoylmaleimide X HCl [145317-11-9] RO 31-8425 C26H24N4O2.HCl AGC PKC - PLCbeta Serine-Threonine TGFb-SMAD - GPCR - BTK
SYN-1022 BMS-2 [888719-03-7] BMS2 C25H16F2N4O3 RTK MET Tyrosine RTK
SYN-1023 BMS-3 [1338247-30-5] BMS3 C17H12Cl2F2N4OS TKL LIMK1 - LIMK2 Serine-Threonine N/A
SYN-1024 BMS-5 [1338247-35-0] BMS5 C17H14Cl2F2N4OS TKL LIMK1 - LIMK2 Serine-Threonine MAP Kinase - GPCR - Epigenetic
SYN-1026 BX795 [702675-74-9] BX795 C23H26IN7O2S AGC PDK1 Serine-Threonine NF-kB - mTOR
SYN-1027 BX912 [702674-56-4] BX912 C20H23BrN8O AGC PDK1 - PI3K Serine-Threonine NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1028 CC-401 HCl [1438391-30-0] CC401 C22H24N6O.HCl CMGC JNK Serine-Threonine TGFb-SMAD - GPCR - BTK - MAP Kinase
SYN-1030 Canertinib  [267243-28-7] CI-1033, PD-183805 C24H25ClFN5O3 RTK EGFR Tyrosine N/A
SYN-1031 CI-1040 [212631-79-3] PD184352, CI1040 C17H14ClF2IN2O2 STE MEK - MKK4&7 - MKK3&6 - MEK5 - MEK2 - MEK1 Serine-Threonine JAK-STAT - MAP Kinase - Epigenetic - TGFb-SMAD
SYN-1033 CP-724714 [383432-38-0] CP724714 C27H27N5O3 RTK HER2 Tyrosine Epigenetic
SYN-1034 CYC116 [693228-63-6] CYC116 C18H20N6OS Other Aurora A Serine-Threonine Cell Cycle
SYN-1035 Momelotinib [1056634-68-4] CYT387, Momelotinib C23H22N6O2 PTK JAK2 Tyrosine JAK-STAT
SYN-1036 Dasatinib [302962-49-8] BMS-354825, Sprycel C22H26ClN7O2S PTK Abl - BCR - BTK Tyrosine Cell Cycle - BTK
SYN-1037 Dianilinopyrimidine_01 [916603-07-1] CZC8004 C17H16FN5 N/A Pan-Tyrosine Kinase Tyrosine N/A
SYN-1038 E7080 [417716-92-8] E7080 C21H19ClN4O4 RTK FGFR - VEGFR - SCF Tyrosine Epigenetic
SYN-1039 Erlotinib HCl [183319-69-9] OSI774, CP-358774, Tarceva, NSC718781 C22H23N3O4.HCl RTK EGFR Tyrosine JAK-STAT - Epigenetic
SYN-1041 GDC-0941 [957054-30-7] GDC0941 C23H27N7O3S2 Lipid Kinase PI3K Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1042 Gefitinib [184475-35-2] ZD1839, Iressa C22H24ClFN4O3 RTK EGFR - HER2 Tyrosine JAK-STAT - Epigenetic
SYN-1044 GW441756 [504433-23-2] GW441756 C17H13N3O RTK TrkA Tyrosine N/A
SYN-1045 IC87114 [371242-69-2] IC87114 C22H19N7O Lipid Kinase PI3K Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1046 Imatinib mesylate [220127-57-1] CGP54148, ST1571, Gleevec,Glivec,Imatinib mesylate C29H31N7O.CH4SO3 PTK Abl - BCR Tyrosine BTK - Cell Cycle
SYN-1047 JNJ-38877605 [943540-75-8] JNJ38877605 C19H13F2N7 RTK c-MET Tyrosine N/A
SYN-1048  JNJ-7706621 [443797-96-4] JNJ7706621 C15H12F2N6O3S Other Aurora A - CDK7 - CDK5 - CDK4 - CDK2 Serine-Threonine Cell Cycle - Epigenetic
SYN-1049 Ki20227 [623142-96-1] Ki20227 C24H24N4O5S RTK c-fms Tyrosine N/A
SYN-1050 KU0063794 [938440-64-3] KU0063794 C25H31N5O4 Atypical (PIKK) mTOR Serine-Threonine N/A
SYN-1051 KU55933 [587871-26-9] KU55933 C21H17NO3S2 Atypical (PIKK) ATM/ATR Serine-Threonine Cell Cycle
SYN-1052 Lapatinib [231277-92-2] GW-572016, Tykerb C29H26ClFN4O4S RTK EGFR Tyrosine JAK-STAT - Epigenetic
SYN-1053 Masatinib [790299-79-5] AB1010, Masivet C28H30N6OS RTK c-Kit, PDGFR and FGFR3 Tyrosine N/A
SYN-1054 Merck 5 [457081-03-7] Merck 5 C18H16FN3O PTK JAK Tyrosine JAK-STAT
SYN-1055 Motesanib  [453562-69-1] AMG706 C22H23N5O RTK PDGFR Tyrosine Epigenetic
SYN-1056 Amuvatinib [850879-09-3] MP-470 C23H21N5O3S RTK PDGFR Tyrosine Epigenetic - NF-kB - TGFb-SMAD - JAK-STAT
SYN-1057 Nilotinib [641571-10-0] AMN107, Tasigna C28H22F3N7O RTK, PTK Abl - PDGFR - BCR Tyrosine BTK - Cell Cycle - Epigenetic
SYN-1058A Pazopanib HCl [635702-64-6] GW786034, Votrient, Armala C21H23N7O2S.HCl RTK PDGFR Tyrosine N/A
SYN-1060 PF04217903 [956905-27-4] PF04217903 C19H16N8O RTK MET Tyrosine N/A
SYN-1061 PD173955 [260415-63-2] PD173955 C21H16Cl2N4OS PTK Abl - BCR Tyrosine BTK - Cell Cycle
SYN-1062 PD173955-Analog1 [185039-99-0] PD-173955-Analog1 C21H14Cl2N4O3 PTK Abl - BCR - Src Tyrosine BTK - Cell Cycle
SYN-1064 PF-562271 [717907-75-0] PF562271 C21H20F3N7O3S RTK FAK, PYK2, PTK Tyrosine Epigenetic
SYN-1065 PI103 [371935-74-9] PI103 C19H16N4O3 Lipid Kinase PI3K - AKT - mTOR Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1066 PIK-93 [593960-11-3] PIK93 C14H16ClN3O4S2 Lipid Kinase PI3K Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1067 PIK-75 [372196-67-3] PIK75 C16H14BrN5O4S Lipid Kinase PI3K Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1068 PIK-90 [677338-12-4] PIK90 C18H17N5O3 Lipid Kinase PI3K Lipid N/A
SYN-1069 PLX4720 [918505-84-7] PLX4720 C17H14ClF2N3O3S TKL ARaf - Raf - CRaf - BRaf Tyrosine MAP Kinase - GPCR - Epigenetic
SYN-1070 Purvalanol B [212844-54-7] NG95 C20H25ClN6O3 CMGC CDK2 - CDK7 - CDK5 - CDK4 Serine-Threonine Cell Cycle - Epigenetic
SYN-1071 GSK429286A [864082-47-3] GSK429286A, RHO-15 C21H16F4N4O2 AGC ROCK Serine-Threonine N/A
SYN-1072 RWJ-67657 [215303-72-3] RWJ67657 C27H24FN3O CMGC p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1073 SB202190 [152121-30-7] SB202190 C20H14FN3O CMGC p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1073A SB202190 HCl [350228-36-3] SB202190 HCl C20H14FN3O.HCl CMGC p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1074 SB203580 [152121-47-6] RWJ 64809, PB 203580 C21H16FN3OS CMGC p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1075 SB-216763 [280744-09-4] SB216763 C19H12Cl2N2O2 RTK HER2 Tyrosine Epigenetic
SYN-1076 SB-242235 [193746-75-7] SB242235 C19H20FN5O CMGC p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1077 SB590885 [405554-55-4] SB590885 C27H27N5O2 TKL ARaf - Raf - CRaf - BRaf Serine-Threonine MAP Kinase - GPCR - Epigenetic
SYN-1078 SD-06 [271576-80-8] SD06 C20H20ClN5O2 CMGC p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1079 SD169 [1670-87-7] SD169 C9H8N2O CMGC MAPK - p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1080 BMS387032 HCl [345627-90-9] BMS387032, SNS-032 C17H24N4O2S2.HCl CMGC CDK2 - CDK7 - CDK5 - CDK4 Serine-Threonine Cell Cycle - Epigenetic
SYN-1081 SNS-314 [1057249-41-8] SNS314 C18H15ClN6OS2 Other Aurora A Serine-Threonine Cell Cycle
SYN-1083 SR3677 [1072959-67-1] SR3677 C22H24N4O4 AGC RSK Serine-Threonine N/A
SYN-1085 SU-6668 [252916-29-3] SU6668 C18H18N2O3 RTK FGFR - PDGFR Tyrosine Epigenetic
SYN-1087 TAK-715 [303162-79-0] TAK715 C24H21N3OS CMGC p38 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1088 Tandutinib [387867-13-2] CT53518, MLN518 C31H42N6O4 RTK PDGFR Tyrosine Epigenetic
SYN-1089 TGX221 [663619-89-4] TGX-221 C21H24N4O2 Lipid Kinase PI3K Lipid NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1090 Vandetanib [443913-73-3] ZD6474, Zactima, Vandetanib C22H24BrFN4O2 RTK EGFR - HER2 Tyrosine JAK-STAT - Epigenetic 
SYN-1091 Intedanib [656247-17-5] Intedanib,BIBF 1120, Vargatef  C31H33N5O4 RTK FGFR - PDGFR Tyrosine Epigenetic
SYN-1092 Tozasertib  [639089-54-6] MK-0457, VX-680 C23H28N8OS Other Aurora A Serine-Threonine Cell Cycle
SYN-1093 VX-702 [745833-23-2] VX702 C19H12F4N4O2 CMGC P38 Serine-Threonine MAP Kinase - GPCR - BTK
SYN-1094 YM201636 HCl [371942-69-7 (free base)] YM201636 C25H21N7O3.HCl Lipid Kinase PIKfyve Lipid N/A
SYN-1095 Danusertib [827318-97-8] PHA-739358 C26H30N6O3 Other Abl - Aurora A - BCR - FGFR Serine-Threonine TGFb-SMAD - BTK - Cell Cycle - Epigenetic
SYN-1098 PIK-294 [900185-02-6] PIK294 C28H23N7O2 Lipid Kinase PI3K Lipid NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1099 ZSTK474 [475110-96-4] ZSTK474 C19H21F2N7O2 Lipid Kinase PI3K Lipid NF-kB - mTOR - TGFb-SMAD - JAK-STAT
SYN-1100 Afatinib [439081-18-2] Tovok, BIBW-2992 C24H25ClFN5O3 RTK EGFR - HER2 Tyrosine JAK-STAT - Epigenetic
SYN-1101 R1487 HCl [449808-64-4] SY-R1487 C19H18F2N4O3.HCl CMGC p38 Serine-Threonine N/A
SYN-1103 TG101209 [936091-14-4] TG101209 C26H35N7O2S PTK JAK2 Tyrosine JAK-STAT
SYN-1104 Fedratinib [936091-26-8] SAR-302503, SAR302503, TG101348 C27H36N6O3S PTK JAK Tyrosine JAK-STAT
SYN-1105 TG100115 [677297-51-7] TG100115 C18H14N6O2 Lipid Kinase PI3K Lipid N/A
SYN-1106 TG-46 [936091-15-5] TG46 C26H34N6O3S PTK JAK Tyrosine JAK-STAT
SYN-1107 TG-89 [936091-56-4] TG89 C26H34N6O3S PTK JAK2 Tyrosine JAK-STAT
SYN-1108 LY294002 [154447-36-6] LY294002 C19H17NO3 Lipid Kinase PI3K Lipid NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1109 CX-4945 [1009820-21-6] CX4945 C19H12ClN3O2 CAMK Chk2 Serine-Threonine Cell Cycle
SYN-1110 A-674563 HCl [552325-73-2 (free base)] A674563 C22H22N4O.HCl AGC AKT - PKA - CDK7 - CDK5 - CDK4 - CDK2 Serine-Threonine NF-kB - Epigenetic - GPCR - Cell Cycle - BTK - mTOR - JAK-STAT - TGFb-SMAD
SYN-1111 AMG-51 [890019-63-3] AMG51 C34H33F2N5O5 Atypical (PIKK) mTOR Serine-Threonine TGFb-SMAD - mTOR - JAK-STAT
SYN-1112 Mubritinib [366017-09-6] TAK-165 C25H23F3N4O2 PTK HER2 Tyrosine HER2
SYN-1113 SMI-4a [438190-29-5] SMI4a C11H6F3NO2S CAMK PIM Serine-Threonine N/A
SYN-1114 GNE-490 [1033739-92-2] GNE490 C18H22N6O2S Lipid Kinase PI3K Lipid NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1115 GNE-493 [1033735-94-2] GNE493 C17H20N6O2S Lipid Kinase PI3K Lipid NF-kB - JAK-STAT - mTOR - TGFb-SMAD
SYN-1116 Ponatinib [943319-70-8] AP24534 C29H27F3N6O PTK Abl - BCR - FGFR Tyrosine BTK - Cell Cycle - Epigenetic
SYN-1117 Baricitinib phosphate [1187595-84-1] LY3009104, INCB-28050 C16H17N7O2S.H3PO4 PTK JAK Tyrosine JAK-STAT
SYN-1119 S-99 [1124381-69-6] S99 C16H15F3N6O STE ASK Serine-Threonine N/A
SYN-1120 Ruxolitinib [941678-49-5] INCB018424 C17H18N6 PTK JAK Tyrosine JAK-STAT
SYN-1121 R406 [841290-80-0] R406 C22H23FN6O5 PTK Syk Tyrosine N/A
SYN-1122 R788 disodium [1025687-58-4] Fostamatinib, FosD, tamatinib fosdium, R788 C23H24FN6O9P.2Na PTK BCR Tyrosine N/A
SYN-1123 VX745 [209410-46-8] VX745 C19H9Cl2F2N3OS CMGC MAPK Serine-Threonine MAP Kinase
SYN-1124 GSK-25 [874119-56-9] GSK25 C24H16Cl2F2N6O AGC RSK1 - p70S6K Serine-Threonine N/A
SYN-1125 AMG-25 [1003311-62-3] AMG25 C23H17N5O2 RTK PDGFR Tyrosine Epigenetic
SYN-1126 GSK2126458 [1086062-66-9] HYR-582 C25H17F2N5O3S Lipid Kinase PI3K Lipid NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1128 RO495 [1258296-60-4] RO495 C17H14Cl2N6O PTK TYK2 Tyrosine NF-kB
SYN-1129 Foretinib [849217-64-7] GSK1363089, Foretinib, EXEL-2880, XL880 C34H34F2N4O6 RTK VEGFR2 - MET Tyrosine MAP Kinase - GPCR - BTK
SYN-1130 Bayer-18 [1251752-12-1] Bayer18 C19H27FN6O2 RTK TYK2 Tyrosine N/A
SYN-1131 R428 [1037624-75-1] R428 C30H34N8 AGC AKT Serine-Threonine N/A
SYN-1132 S6K-18 [1265789-88-5] S6K18 C17H18N4O3S AGC S6K Serine-Threonine TGFb-SMAD - mTOR 
SYN-1133 JNJ-38158471 [951151-97-6] JNJ38158471 C15H17ClN6O3 RTK VEGFR-2 Tyrosine N/A
SYN-1134 Brivanib [649735-46-6] BMS540215, Brivanib C19H19FN4O3 RTK FGFR Tyrosine Epigenetic
SYN-1135 Brivanib alaninate [649735-63-7] Brivanib alaninate C22H24FN5O4 RTK FGFR Tyrosine Epigenetic
SYN-1136 NVP-BSK805 2HCl [1092499-93-8] NVP-BSK805, BSK-805 C27H28F2N6O.2HCl PTK JAK2 Tyrosine JAK-STAT
SYN-1137 XL765 [1349796-36-6] SAR245409 C31H29N5O6S Lipid Kinase PI3K Lipid NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1138 Cabozantinib [849217-68-1] XL184, BMS-907351 C28H24FN3O5 RTK PDGFR Tyrosine Epigenetic
SYN-1140 Neratinib [698387-09-6] HKI-272 C30H29ClN6O3 RTK EGFR Tyrosine N/A
SYN-1141 Pelitinib [257933-82-7] EKB-569 C24H23ClFN5O2 RTK EGFR - HER2 Tyrosine JAK-STAT - Epigenetic 
SYN-1142 BMS-599626 [714971-09-2] AC480, BMS599626, AC-480 C27H27FN8O3 RTK EGFR - HER2 Tyrosine JAK-STAT - Epigenetic 
SYN-1143 AMG-1 [913376-84-8] AMG1 C31H29FN4O5 RTK c-Met - RON Tyrosine NF-kB - MAP Kinase - Epigenetic
SYN-1144 AMG-458 [913376-83-7] AMG458 C30H29N5O5 Atypical (PIKK) mTOR Serine-Threonine TGFb-SMAD - mTOR - JAK-STAT
SYN-1145 NIBR-17 [944396-88-7] NIBR17 C18H20N8O2 Lipid Kinase PI3K Lipid NF-kB - mTOR - JAK-STAT - TGFb-SMAD
SYN-1146 CH5132799 [1007207-67-1] CH5132799 C15H19N7O3S Lipid Kinase PI3K - mTOR Lipid NF-kB - TGFb-SMAD - mTOR - mTOR - JAK-STAT - TGFb-SMAD
SYN-1147 Bentamapimod [848344-36-5] Bentamapimod, AS-602801 C25H23N5O2S RTK PDGFR Tyrosine Epigenetic
SYN-1148 GNE 477 [1032754-81-6] GNE 477 C21H28N8O3S2 Lipid Kinase PI3K Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1149 MK-2461 [917879-39-1] MK2461 C24H25N5O5S RTK FGFR Tyrosine Epigenetic
SYN-1150 RG7422 [1032754-93-0] RG7422, GDC0980 C23H30N8O3S Lipid Kinase PI3K Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1152 NVP-BGJ398 [872511-34-7] NVP-BGJ398, BGJ-398 C26H31Cl2N7O3 RTK FGFR Tyrosine Epigenetic
SYN-1153 TAK-285 [871026-44-7] TAK285 C26H25ClF3N5O3 RTK EGFR - HER2 Tyrosine JAK-STAT - Epigenetic 
SYN-1154 JNJ-28312141 [885692-52-4] JNJ28312141 C26H32N6O2 CMGC cFMS Serine-Threonine NF-kB - mTOR - BTK
SYN-1155 SGX523 [1072116-01-8] SGX523 C18H13N7S RTK c-Met Tyrosine TGFb-SMAD - mTOR - JAK-STAT
SYN-1156 CEP-33779 [1346168-57-7] CEP33779 C24H26N6O2S PTK JAK Tyrosine JAK-STAT
SYN-1157 MLN0128 [1224844-38-5] MLN0128, INK-128 C15H15N7O STE MEK - MEK5 - MEK2 - MEK1 Serine-Threonine TGFb-SMAD - JAK-STAT - MAP Kinase - Epigenetic
SYN-1158 GLPG0634 [1206161-97-8] GLPG0634 C21H23N5O3S PTK JAK1 - JAK2 Tyrosine JAK-STAT
SYN-1159 TAE684 [761439-42-3] TAE684, NVP-TAE684 C30H40ClN7O3S RTK ALK Tyrosine N/A
SYN-1160 AZD-26 [1357158-81-6] AZD26 C22H21N3O AGC AKT Serine-Threonine NF-kB - BTK - mTOR - JAK-STAT - TGFb-SMAD 
SYN-1161 PLX4032 [918504-65-1] Vemurafenib, RG7204, Zelboraf, RO5185426 C23H18ClF2N3O3S TKL Raf Serine-Threonine TGFb-SMAD - GPCR - JAK-STAT
SYN-1162 MK-2206 2HCl [1032350-13-2] MK-2206 2HCl C25H21N5O.2HCl AGC AKT Serine-Threonine NF-kB - BTK - mTOR - JAK-STAT - TGFb-SMAD 
SYN-1163 PF4618433 [1166393-85-6] PF-4618433 C24H27N7O2 PTK PYK2 - FAK Tyrosine N/A
SYN-1164 GCI1746 [910232-84-7] G-182 C34H37N5O4 PTK BTK Tyrosine BTK
SYN-1165 SAR131675 [1092539-44-0] SAR131675 C18H22N4O4 RTK VEGFR-3 Tyrosine N/A
SYN-1166 AZD8055 [1009298-09-2] CCG 168 C25H31N5O4 Atypical (PIKK) mTOR Serine-Threonine JAK-STAT - mTOR
SYN-1167 AZD2014 [1009298-59-2] AZD2014 C25H30N6O3 Atypical (PIKK) mTOR Serine-Threonine JAK-STAT - mTOR
SYN-1168 Takeda-6d [1125632-93-0] Takeda-6d C27H19ClFN5O3S TKL B-RAF - VEGFR2 Serine-Threonine MAP Kinase - BTK - GPCR
SYN-1169 Regorafenib [755037-03-7] BAY 73-4506 C21H15ClF4N4O3 RTK VEGFR Tyrosine N/A
SYN-1170 GSK1120212 [871700-17-3] JTP-74057, GSK212, Trametinib C26H23FIN5O4 STE MEK1 - MEK2 Serine-Threonine N/A
SYN-1171 Ibrutinib [936563-96-1] PCI-32765 C25H24N6O2 PTK BTK Tyrosine BTK
SYN-1172 Ruboxistaurin HCl [169939-93-9] LY333531 C28H28N4O3.HCl AGC PKC Serine-Threonine N/A
SYN-1173 SCH 900776 [891494-63-6] SCH 900776 C15H18BrN7 CAMK Chk1 - Chk2 Serine-Threonine Cell Cycle
SYN-1174 PF0477736 [952021-60-2] PF0477736 C22H25N7O2 CAMK Chk1 Serine-Threonine N/A
SYN-1175 IPI 145 [1201438-56-3] IPI 145 C22H17ClN6O Atypical (PIKK) mTOR - PI3K Serine-Threonine NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1178 BGT-226 maleate [1245537-68-1] BGT226 C28H25F3N6O2.C4H4O4 Lipid Kinase PI3K Lipid N/A
SYN-1179 Bafetinib [859212-16-1] NS-187, INNO-406 C30H31F3N8O PTK BCR Tyrosine BTK
SYN-1181 PP242 [1092351-67-1] PP242 C16H16N6O STE MEK - MEK5 - MEK2 - MEK1 Serine-Threonine N/A
SYN-1182 CX6258 [1202916-90-2] CX6258 C26H24ClN3O3 STE PKC - PKCalpha Serine-Threonine NF-kB - TGFb-SMAD - BTK - GPCR
SYN-1183 GNF-5837 [1033769-28-6] GNF5837 C28H21F4N5O2 RTK TRK Serine-Threonine N/A
SYN-1186 XL388 [1251156-08-7] XL388 C23H22FN3O4S CAMK Chk1 Serine-Threonine TGFb-SMAD - JAK-STAT - mTOR
SYN-1187 MPI0479605 HCl [1246529-32-7 (free base)] MPI0479605 C22H30ClN7O.HCl STE MEK - MEK5 Serine-Threonine N/A
SYN-1188 CH4987655 [874101-00-5] CH4987655 C20H19F3IN3O5 PTK MEK Tyrosine TGFb-SMAD - JAK-STAT - MAP Kinase /Epigenetic
SYN-1189 SAR020106 [1184843-57-9] SAR020106 C19H19ClN6O RTK EGFR - HER2 Tyrosine Cell Cycle
SYN-1190 AS703026 [1236699-92-5] AS703026 C15H15FIN3O3 STE MEK1 - MEK2 Serine-Threonine TGFb-SMAD /JAK-STAT /MAP Kinase /Epigenetic
SYN-1191 XL019 [945750-13-0] XL019 C25H28N6O2 Lipid Kinase PI3K - mTOR Lipid JAK-STAT
SYN-1193 SGI-1776  [1025065-69-3] SGI1776  C20H22F3N5O CAMK Pim1 - Pim2 - Pim3 Serine-Threonine N/A
SYN-1194 PF-04979064  [1220699-06-8] PF04979064  C24H26N6O3 Lipid Kinase PI3K - mTOR Lipid NF-kB - TGFb-SMAD - JAK-STAT - mTOR
SYN-1195 AZD8330 [1204531-17-8] AZD8330 C16H17FIN3O4 STE MEK1 - MEK2 Serine-Threonine TGFb-SMAD - JAK-STAT - MAP Kinase - Epigenetic
SYN-1196 LY2784544 [1229236-86-5] LY2784544 C23H25ClFN7O PTK JAK2 Tyrosine JAK-STAT
SYN-1197 BLZ-945 [953769-46-5] BLZ945 C20H22N4O3S PTK c-FMS Tyrosine N/A
SYN-1198 GDC-046 [1258292-64-6] GDC046 C16H13Cl2N3O2 PTK TYK2 Tyrosine N/A
SYN-1199 LDK378 [1032900-25-6] LDK378 C28H36ClN5O3S RTK ALK Tyrosine N/A
SYN-1200 BKM120 [944396-07-0] BKM120 C18H21F3N6O2 Lipid Kinase PI3K - mTOR Lipid PI3K - mTOR
SYN-1201 GSK2606414 [1337531-36-8] GSK2606414 C24H20F3N5O Other PERK Serine-Threonine N/A
SYN-1202 GDC-0032 [1282512-48-4] GDC0032 C24H28N8O2 Lipid Kinases PI3K Lipid N/A
SYN-1203 TAK632 [1228591-30-7] TAK632 C27H18F4N4O3S TKL Raf Serine-Threonine N/A
SYN-1204 PRT-060318 [1194961-19-7] PRT060318, PRT318 C18H24N6O PTK Syk Tyrosine N/A
SYN-1205 KW-2449 HCl [1038395-65-1] KW2449 C20H20N4O.HCl  RTK Aurora A - Abl - FGFR - BCR - fms Tyrosine N/A
SYN-1206 VTX-27 [1321924-70-2] VTX27 C20H24ClFN6O    AGC PKCtheta Serine N/A
SYN-1207 CFI-400437 [N/A] N/A C29H28N6O2.2HCl Other PLK4 Serine-Threonine N/A
SYN-1208 TASP0415914 [1292300-75-4] TASP0415914 C13H17N5O3S Atypical PI3Kgamma Lipid N/A
SYN-1210 AST-487  [630124-46-8] NVP-AST 487, AST487  C26H30F3N7O2           TK Flt3 Tyrosine N/A
SYN-1211 URMC-099 [1229582-33-5] URMC099 C27H27N5 TKL MLK3 - LRRK Tyrosine MAPK - JUN
SYN-1212 SP2509 [1423715-09-6] SP2509, SP-2509 C19H20ClN3O5S N/A LSD1 N/A N/A
SYN-1213 LEE011 [1211441-98-3] LEE-011 C23H30N8O CGMC CDK4 - CDK6 Serine-Threonine Cell Cycle - Epigenetic
SYN-1214 AZD1208 [1204144-28-4] AZD-1208 C21H21N3O2S CAMK PIM Serine-Threonine N/A
SYN-1215 GW806742X [N/A] GW806742X, AC1NS7PT, AGN-PC-0LQ49Y, Compound 1 C25H22F3N7O4S RTK VEGFR2 - YES - MLKL Tyrosine Necrosis - Necroptosis
SYN-1216 CCT244747 [1404095-34-6] CCT244747 C20H24N8O2 CAMK CHK1 Serine-Threonine N/A
SYN-1217 S49076 HCl [1265965-19-2] S-49076 C22H23ClN4O4S TK MET, AXL, FGFR Tyrosine N/A
SYN-1219 GSK-A1 [1416334-69-4] GSKA1 C29H27FN6O4S PIKK PI4KA Serine-Threonine N/A
SYN-1220 GSK-F1 [1402345-92-9] GSKF1 C27H18F5N5O4S PIKK PI4KA Serine-Threonine N/A
SYN-1221 H1152 [871543-07-6] H-1152 C16H21N3O2S.2HCl AGC ROCK Serine-Threonine N/A
SYN-1222 LY2801653 [1206799-15-6] LY-2801653 C30H22F2N6O3 RTK c-MET Tyrosine N/A
SYN-1225 BBT594 [882405-89-2] NVP-BBT594 C28H30F3N7O3 PTK JAK2 Tyrosine JAK-STAT
SYN-1226 BGG463 [890129-26-7] NVP-BGG463 C30H29F3N6O3 PTK Src - Abl Tyrosine BTK - Cell Cycle
SYN-1227 MBP146-78 [188343-77-3] MBP146-78 C21H22FN3 AGC PKG Serine-Threonine N/A
SYN-1228 BIX02565 [1311367-27-7] BIX-02565 C26H30N6O2 AGC RSK2 Serine-Threonine N/A
SYN-1229 Selonsertib Hydrochloride [1448428-05-4] Selonsertib, GS-4997 C24H25ClFN7O.HCl STE ASK1 Serine-Threonine N/A
SYN-1230 Alpelisib [1217486-61-7] BYL719 , NVP-BYL719 C19H22F3N5O2S Lipid Kinase  PI3Kalpha Lipid NF-kB - mTOR - JAK-STAT
SYN-1231 Selonsertib [1448428-04-3] GS-4997 C24H24FN7O STE ASK1 Serine-Threonine N/A
SYN-1232 Abemaciclib [1231929-97-7]  LY2835219 C27H32F2N8 CGMC CDK4/CDK6 N/A N/A
SYN-1233 Nutlin-3a [675576-98-4] Nutlin-3a C30H30Cl2N4O4   N/A MDM2-p53 N/A N/A
SYN-1234 CPI-637 [1884712-47-3] CPI-637 C22H22N6O    N/A CBP/EP300 N/A N/A
SYN-1235 Eleclazine hydrochloride [1448754-43-5] GS-6615 hydrochloride C21H17ClF3N3O3    N/A N/A N/A N/A
SYN-1236 Ridaifen B [886465-70-9] Ridaifen B C34H42N2O2  N/A N/A N/A N/A
SYN-1237 BLU9931 [1538604-68-0] BLU9931 C26H22Cl2N4O3 N/A FGFR4 N/A N/A
SYN-1278 GSK481 [1622849-58-4] GSK481  C21H19N3O4 N/A RIPK1 N/A N/A
SYN-1279 Neratinib [698387-09-6] HKI-272 C30H29ClN6O3 N/A HER2 and EGFR N/A N/A
SYN-1280 Dinaciclib   [779353-01-4] SCH 727965 C21H28N6O2 N/A CDK N/A N/A
SYN-1281 Erdafitinib [1346242-81-6] JNJ-42756493 C25H30N6O2 N/A FGFR N/A N/A
SYN-1282 S63845 [1799633-27-4] S63845 C39H37ClF4N6O6S N/A MCL-1  N/A N/A
SYN-1283 Pexidartinib  [1029044-16-3] PLX3397 C20H15ClF3N5  N/A CSF-1R, Kit, and FLT3 N/A N/A
SYN-1284 Entrectinib  [1108743-60-7] RXDX-101, NMS-E628 C31H34F2N6O2  N/A pan-TrkA/B/C, ROS1 and ALK N/A N/A
SYN-1285 Bay-293 [2244904-70-7] Bay-293 C25H28N4O2S  N/A SOS1  N/A N/A
SYN-1286 Rabusertib  [911222-45-2] LY2603618 C18H22BrN5O3  N/A Chk1 N/A N/A
SYN-1287 Lorlatinib   [1454846-35-5] PF-06463922 C21H19FN6O2  N/A ROS1/ALK N/A N/A
SYN-1288 CC-220 [1323403-33-3] Iberdomide C25H27N3O5   N/A Cereblon N/A N/A
SYN-1289 Remibrutinib  [1787294-07-8] LOU064 C27H27F2N5O3   N/A BTK N/A N/A
SYN-1290 BAY 1161909  [1443763-60-7] Empersertib C29H26FN5O4S N/A Mps1  N/A N/A
SYN-1291 BAY-985 [2409479-29-2] BAY-985 C27H30F3N9O   N/A TBK1/IKKε N/A N/A
SYN-1292 VU6015929 [N/A] VU6015929 C24H19F4N5O2 N/A DDR1/2 N/A N/A
SYN-1293 RK-287107 [2171386-10-8] RK-287107 C22H26F2N4O2   N/A tankyrase N/A N/A
SYN-1294 ARS-853 [1629268-00-3] ARS853 C22H29ClN4O3    N/A KRAS(G12C) N/A N/A
SYN-1295 6H05  [1469338-01-9] 6H05  C20H30ClN3O2S3   N/A K-Ras(G12C) N/A N/A
SYN-1296 ONO-7475 [1646839-59-9] ONO-7475 C32H26N4O6   N/A Axl/Mer N/A N/A
SYN-1297 S6821 [1119831-25-2] S6821 C19H19N5O4   N/A TAS2R8  N/A N/A
SYN-1298 Lanraplenib [1800046-95-0] GS-9876 C23H25N9O  N/A SYK  N/A N/A
SYN-1299 Parsaclisib [1426698-88-5] Parsaclisib C20H22ClFN6O2 N/A PI3Kδ  N/A N/A
SYN-3001 Ombrabulin  [253426-24-3]  AVE8062 (hydrochloride); AC7700 (hydrochloride) C21H27ClN2O6 N/A " 
tubulin" N/A N/A
SYN-3002 ER 172594-06 HBr [474550-69-1] Atopaxar hydrobromide, ER172594-06, E5555, ER17259406 C29H38FN3O5 N/A N/A N/A GPCR
SYN-3003 GANT61                   [ 500579-04-4] NSC 136476 C27H35N5 N/A Gli1 /Gli2 N/A N/A
SYN-3004 (+)-JQ1 [ 1268524-70-4] (+)-JQ1 C23H25ClN4O2S N/A BET bromodomain N/A N/A
SYN-3005 PF8380 [1144035-53-9] PF8380 C22H21Cl2N3O5 N/A autotaxin  N/A N/A
SYN-3006 Vorinostat [149647-78-9] SAHA, MK0683, Zolinza C14H20N2O3 N/A HDAC1, HDAC2, HDAC3 N/A N/A
SYN-3029 Quisinostat [875320-29-9] JNJ-26481585, JNJ26481585 C21H26N6O2 N/A HDAC1, 2, 4, 10 and HDAC11 N/A N/A
SYN-3030 GSK-J1 [1373422-53-7] GSKJ1, SYN-5431 C22H23N5O2 N/A JMJD3 - UTX  N/A N/A
SYN-3031 CX-5461 [1138549-36-6] CX5461 C27H27N7O2S N/A N/A N/A N/A
SYN-3033 I-BET762 [1260907-17-2] GSK525762, GSK525762A, GSK-525762, GSK-525762A C22H22ClN5O2 N/A BRD2, BRD3, and BRD4 N/A N/A
SYN-3034 PRIMA-1MET [5291-32-7]  APR-246 C10H17NO3                     N/A p53 N/A N/A
SYN-3035 BI SF3 [118511-97-0] BI SF3 C8H8ClN3                     N/A N/A N/A N/A
SYN-3037 RG 108  [48208-26-0] N-Phthalyl-L-tryptophan C19H14N2O4  N/A DNMTs N/A N/A
SYN-3040 MPI_5a [1259296-46-2] MPI5a, SYN-1218 C16H17N3O3 N/A HDAC6 N/A N/A
SYN-3041 PFI-1 [1403764-72-6] PF-6405761 C16H17N3O4S N/A BET N/A N/A
SYN-3042 Tubastatin A HCl [1310693-92-5] Tubastatin A, SYN-1224 C20H22ClN3O2 N/A HDAC6 N/A N/A
SYN-3043 Olaparib [763113-22-0] AZD2281, AZD-2281 C24H23FN4O3 N/A PARP N/A N/A
SYN-3044 EPZ015666 [1616391-65-1] EPZ-015666 C20H25N5O3 N/A PRMT5 N/A N/A
SYN-3045 EPZ-6438 [1403254-99-8] EPZ6438 C34H44N4O4 N/A EZH2 N/A N/A
SYN-3046 AZ9482 [1825345-33-2] AZ-9482 C26H22N6O2 N/A PARP N/A N/A
SYN-3047 PFI-4 [900305-37-5] PFI4 C21H24N4O3 N/A BRPF1 N/A N/A
SYN-3048 XD14 [1370888-71-3] XD-14 C20H27N3O5S N/A BRD2 - BRD3 - BRD4 N/A N/A
SYN-3049 I-BRD9 [1714146-59-4  ] I-BRD9 C22H22F3N3O3S2 N/A BRD9 N/A N/A
SYN-3050 EPZ005687 [1396772-26-1] EPZ005687 C32H37N5O3 N/A EZH2 N/A N/A
SYN-4001 KiNet-1  [1439934-41-4] CTx-0294885  C22H24ClN7O N/A Akt N/A N/A
SYN-5698 AZD-1775  [955365-80-7] MK-1775 C27H32N8O2  N/A Wee1  N/A N/A
SYN-5740 VE-822 [1232416-25-9] VE-822  C24H25N5O3S  N/A ATR N/A N/A
SYN-5755 AZD-4547 [1035270-39-3] AZD-4547 C26H33N5O3   N/A FGFR N/A N/A

 

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