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Natural Products of Inula Britannica L.

PubMed Reference
Wiki Abstract

 

Inula Britannica, the British yellowhead or meadow fleabane, is a plant species in the genus Inula. The plant produces the flavonol axillarin.
Herbs, perennial, 10-40(-75) cm tall. Stems erect, villous. Leaves sessile; basal blades lanceolate, (3-)6-7 cm × 8-20(-30) mm; cauline blades lanceolate-elliptic to lanceolate-linear, 2-5+ cm × 5-12(-20) mm, abaxially usually densely villous and glandular, adaxially sparsely strigillose to glabrate, bases cordate or auriculate, clasping, margins entire or serrulate. Capitula 1-8, 2.5-5 cm in diam.; peduncles 1-4 cm, densely villous.
Cytotoxicity-guided fractionation of the flowers of Inula britannica led to the isolation of four sesquiterpene lactones, 4 alpha, 6 alpha-dihydroxyeudesman-8 beta, 12-olide (1), ergolide (2), 8-epi-helenalin (3), and bigelovin (4). Compound 1 was isolated as a new natural product. These compounds showed cytotoxicity against human tumor cell lines.

 

Catalog           Product Name                                                                        CAS Number           Manual

CFN90219 1-O-Acetyl britannilactone 681457-46-5   n/a
CFN99272 Quercetin 117-39-5   PDF
CFN99825 Carabrone 1748-81-8   PDF
CFN97104 Taraxasterol acetate 6426-43-3   PDF
CFN98748 alpha-Spinasterol 481-18-5   PDF
CFN98692 alpha-Spinasterol acetate 4651-46-1   n/a
CFN99824 alpha-Spinasterol glucoside 1745-36-4   PDF
CFN99115 6,7-Dihydroxycoumarin 305-01-1   PDF
CFN99952 Daphnetin 486-35-1   PDF
CFN97494 Scopoletin 92-61-5   PDF
CFN98857 Wedelolactone 524-12-9   PDF
CFN98850 Quercitrin 522-12-3   PDF
CFN98753 Isoquercitrin 482-35-9   PDF
CFN99116 Chlorogenic acid 327-97-9   PDF
CFN99074 Taraxasterol 1059-14-9   PDF
CFN89438 1-O-Acetylbritannilactone 33627-41-7   n/a
CFN89470 1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone 1932687-71-2   n/a
CFN89518 1,6-O,O-Diacetylbritannilactone 1286694-67-4   n/a
CFN89521 1-O-Acetyl-6-O-isobutyrylbritannilactone 1613152-34-3   n/a
CFN89001 6alpha-Hydroxytomentosin 1232676-22-0   n/a
CFN89501 Dibritannilactone B 1829580-18-8   n/a
CFN89045 Eupatolide 6750-25-0   n/a

 

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