티스토리 뷰
[미세신경섬유 경쇄/뉴로필라멘트 라이트 체인 정량/측정 효소면역분석법] NF-Light ELISA Assay kit - Research Use Only (RUO) [10-7002 RUO]_UmanDiagnostics AB - 코아사이언스
코피디 2021. 8. 24. 16:31Efficient and accurate detection of brain disease with NF-light®
NF-Light ELISA Assay kit - Research Use Only (RUO)
Cat.# 10-7002 RUO / Size: kit (for one 96-well strip plate)
The NF-light® (Neurofilament light) ELISA allows fast quantification (<3 hours) of neurofilment light in cerebrospinal fluid. The amount of sample is small (50 μl) and the standard curve ranges from 100 – 10000 pg/ml allowing for direct measurements of NF-L in many different neurological conditions.
Immunoassay for quantitative determinations
Neurofilaments constitutes the backbone of the neuronal cytoskeleton and are important for the maintenance of the axonal calibre and thereby the velocity of nerve impulses. Neurofilament light is the quantitative most common of the three different neurofilament chains. When the axon is damaged due to direct trauma or slow degenerative processes the content leaks out to the surrounding tissue. Neurofilament light has been shown to be present in cerebrospinal fluid from patients with diseases affecting the white matter. Typical disease are Multiple Sclerosis, Amyotrophic Lateral Sclerosis and Parkinsons disease.
References
Read more about NF-light® and the use of UmanDiagnostics’ antibodies in research
Standard range | 100-10000 pg/ml |
Specimen /volumes | 50 μl CSF |
Method | ELISA |
Substrate | TMB |
For research use only! Not for use in diagnostic procedures.
coresciences 코아사이언스 UmanDiagnostics AB Korea distributor 코리아 한국대리점 항체 ELISA kits 단백질 NF-light Neurofilament light 바이오마커 biomarker 알츠하이머 치매 신경염증 신경퇴화 반영인자 Neurofilament light chain NfL 미세신경섬유 경쇄 뉴로필라멘트 라이트 체인 뇌척수액 CSF 다발성경화증 파킨슨병 Traumatic brain injury slow neurodegenerative brain disease brain disease 뇌질환 뇌질병 진단 연구 예측 NF-light™ ELISA RUO Uman NF-light® ELISA assay
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