[Institute of Microbial Chemistry (BIKAKEN)] Bioactive Compounds_Funakoshi - 코아사이언스

Institute of Microbial Chemistry (BIKAKEN)

Bioactive Compounds

 

Bioactive compounds listed here are produced by the Institute of Microbial Chemistry (BIKAKEN). These products are useful for drug screenings and various pharmacological activity assays (inhibition assays).

​

What is BIKAKEN

The Institute of Microbial Chemistry (BIKAKEN) was established in 1962 using funds raised from royalties from the new antibiotic kanamycin, which was discovered by the late Dr. Hamao Umezawa. The institute has since given rise to numerous beneficial antibiotics, including kasugamycin, which is highly effective against rice blast, and bleomycin, which was the world’s first target-specific anticancer agent. It has continued to conduct research and development on antibacterial agents, anticancer agents, antiviral agents, etc. by microbial drug discovery, as well as organic synthesis research and process research on pharmaceutical products. To date, there have been 14 medicines created by the Institute of Microbial Chemistry, including the antibacterial agents dibekacin and arbekacin, the anticancer agents bleomycin, peplomycin, aclarubicin, the veterinary agents aivlosin, tildipirosin, and the pesticide kasugamycin. BIKAKEN’s unique bioactive compounds from microorganisms are widely used in the world as research reagents and contribute to scientific development.

​

Product Information

Enzyme Inhibitor or Enzyme Resistant Substance

Function	Description	Product Cat.#
Inhibition of DNA helicase	Heliquinomycin	10665
Inhibition of GMP synthase	Oxanosine	00762
Inhibition of NADH (ubiquinone oxidoreductase)	Piericidin A1	14688
Inhibition of NDPK (nucleoside diphosphate kinase)	Cyclamidomycin	01541
Inhibition of α-glucosidase	6-O-Methylreticulol	14693
Inhibition of β-galactosidase	Pyridindolol	00372
Inhibition of alkaline phosphatase	Forphenicin	09636
Inhibition of glyoxalase-I (GloI)	COTC	14675
Inhibition of glutathione S-transferase	Benastatin A	00379
	Benastatin B	14653
	Benastatin C	00380
	Bequinostatin A	14681
	Bequinostatin C	14654
Inhibition of dipeptidyl aminopeptidase	Dioctatin A (Hydrochloride)	14700
Inhibition of dipeptidyl peptidase Ⅲ	Fluostatin A (Sodium Salt)	15403
	Fluostatin B	14683
Inhibition of protein phosphatase 2A	Cytostatin (sodium salt)	10664
	Rubratoxin A	10663
Inhibition of thymidylate synthase	Vanoxonin	10744
Inhibition of tyrosine kinase	Erbstatin	14697
Inhibition of dopamine β-hydroxylase	Dopastin	00381
Inhibition of heparanase	Heparastatin (Hydrochloride) <SF-4>	11829
Inhibition of phospholipase A2	Plipastatin A1	15170
Suppression GRP78 up-regulation	Piericidin A1	14688
Resistance to trehalase	Lentztrehalose A	14678
	Lentztrehalose B	14679
	Lentztrehalose C	14680

Biological Activity

Function	Description	Product Cat.#
Anti-tumor	Altemicidin	12151
	Bactobolin A (Hydrochloride)	08465
	Bisucaberin	14659
	COMC	14701
	COTC	14675
	6-epi-COTC	14698
	Forphenicinol	09637
	Inostamycin A (Sodium Salt)	14652
	Iturin A-2	15171
	Lentztrehalose A	14678
	Migrastatin	10708
	Oxanosine	00762
Metastasis control	Migrastatin	10708
Antimicrobe (gram-positive & negative)	Althiomycin	14660
	Bactobolin A (Hydrochloride)	08465
	Cyclamidomycin	01541
	Negamycin (Sodium Salt)	14662
Anti-gram positive bacteria	Bottromycin A2	00592
Anti-MRSA, Anti-VRE	Bottromycin A2	00592
Anti-resporatory infectious bacteria	Forphenicinol	09637
Acid-fast bacillus growth suppression	Minosaminomycin	02872
Anti-fungal	Benanomicin A	02966
	Benanomicin B	02968
	Iturin A-2	15171
	Plipastatin A1	15170
Inhibition of protein synthesis in bacteria	Althiomycin	14660
	Minosaminomycin	02872
	Negamycin	14662
Pneumocystis pneumonia suppression	Benanomicin A	02966
Anti-HIV-Ⅰ	Benanomicin A	02966
	Benanomicin B	02968
Immunoregulation	Forphenicinol	09637
Inhibition of aflatoxin production	Dioctatin A (Hydrochloride)	14700
Lectin-like function	Benanomicin A	02966
Induced systemic resistance	Iturin A-2	15171
	Plipastatin A1	15170

* 본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

coresciences 코아사이언스 Funakoshi Korea distributor 후나코시 한국대리점