[Dyes & Labeling/Redox Markers/Amine-Reactive] Dicarboxymethylene Blue NHS ester (DCMB-SE) [AF-0201-D005.0-001]_emp Biotech -코아사이언스

Dicarboxymethylene Blue NHS ester (DCMB-SE)

Cat.# AF-0201-D005.0-001 / Size: 5mg

Amine-reactive methylene blue redox marker for electro-active labeling, designed especially for labeling of biomolecules.

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Properties

Molecular Weight:	722,11
Empirical Formula:	C30H32N5O12SCl
Absorption [nm]:	669 ± 3
Emission [nm]:	686 ± 3
ε [M-1 cm-1]:	>53 000
Buffer System for Fluorescence Readings:	TE Buffer, pH 7.6
Solubility:	Acetonitrile
Appearance (colour):	dark blue
Appearance (form):	solid (powder)
Storage:	- 20 °C. Keep dry! Keep away from light, especially in solution!
Trade name:	Dicarboxymethylene blue succinimidyl ester; Dicarboxymethylene blue NHS ester
Reactive Moiety:	NHS ester, reacts with 1° amines to form a stable amide linkage

Description

The amine-reactive methylene blue derivative is used as an electroactive labeling reagent for covalent attachment to proteins and alkylamino modified nucleic acids. Dicarboxymethylene blue contains two activated carboxylic acid functional groups. In addition to its relatively high absorption, DCMB has excellent and validated redox properties and is a good generator for singlet oxygen, making it to a particularly suitable label for electrochemical and photosensitzer applications.

*Absorption and fluorescence emission maxima of dicarboxymethylene blue (DCMB, F-0201) in TE buffer pH 7.6.

Formal Electrode Potential vs. Ag/AgCl (1 M KCl): Ef = -0.216 V

 

* 본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

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