[Magic Building Blocks Series 9] Acetylene group-containing building blocks_ChemScene - 코아사이언스

안녕하세요!

Building Blocks & Bioactive Molecules 전문제조사 ChemScene 수입/공급 업체 코아사이언스 입니다.

 

자세한 상품 정보 및 관련 문의는 전화 02-858-0328 또는 info@coresciences.co.kr로 문의주시기 바랍니다.

감사합니다!

 

Introduction

The acetylene group, recognized for its unique chemical properties, is extensively utilized in bioorthogonal chemistry and medicinal chemistry. It plays a key role in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), enabling selective and bioorthogonal reactions within complex biological environments. These reactions are crucial for the development of imaging and drug delivery. Furthermore, there are many roles that this structural feature can play in drug activity, which include potency enhancement, reactive warhead, nonpolar linear rigid spacer, bioisostere to a wide range of functionalities, and modulation of drug metabolism pharmacokinetic (DMPK) profile. So far, Chemscene has developed many acetylene group-containing building blocks.

 

Acetylene group-containing building blocks

CS-0168988	CS-0819176	CS-W000423	CS-0021839
CS-W006064	CS-0615476	CS-0694332	CS-0612212
CS-0030338	CS-0610652	CS-0636900	CS-0371726

 

Latest Publications Citing Use of ChemScene Products

Nature.
2023 Sep 20
Nat Commun.
2023 Sep 20;14(1):5832
Nat Cancer..
2023 Sep 18
Adv Funct Mater.
2023 Sep 15

코아사이언스 coresciences Chemscene Korea 한국 대리점 Korea distributor pharmaceutical ingredients natural compounds standards