FK 960 [Axon1607][CAS no. 133920-70-4]_Axon Medchem - 코아사이언스

안녕하세요!

Axon Medchem 공식 수입/공급 업체 코아사이언스 입니다.

 

자세한 상품 정보 및 관련 문의는 전화 02-858-0328 또는 info@coresciences.co.kr로 문의주시기 바랍니다.

감사합니다!

 

 

FK 960

Cat.# Axon 1607 / Size: 10mg, 50mg

Chemical name

N-(4-acetylpiperazin-1-yl)-4-fluorobenzamide

​

CAS [133920-70-4]

MF C13H16FN3O2

MW 265.28

Purity: 99%

Soluble in 0.1N HCl(aq) and DMSO

​

Description

Somatostatin receptor agonist and also a 5-HT agonist; FK960 stimulates both serotonin and somatostatin production as a cognitive enhancer. However, its development for Alzheimer's disease (AD) was terminated in 2003

 

References

A Graul et al. FK-960, Congnition Enhancer. Drug. Fut. 1997, 22(8), 830-832.

N Matsuoka and TG Ainer. FK960 [N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide Monohydrate], a Novel Potential Antidementia Drug, Improves Visual Recognition Memory in Rhesus Monkeys... J. Pharmacol. Exp. Ther. 1997, 280(3), 1201-1209.

JP Hodgkiss and JS Kelly. Effect of FK960, a Putative Cognitive Enhancer, on Synaptic Transmission in CA1 Neurons of Rat Hippocampus. J. Pharmacol. Exp. Ther. 2001, 297(2), 620-628.

F Wang et al. Modulation of Ca2+Channel Currents by a Novel Antidementia Drug N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide Monohydrate (FK960) in Rat Hippocampal Neurons. J. Pharmacol. Exp. Ther. 2004, 308 (1), 120-126.

*본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

코아사이언스 coresciences​ Axon medchem 한국 대리점  Ligands small molecule inhibitors or modulators targeting more than 850 biological targets of cell signaling, gene transcription, apoptosis, cell cycle regulation, CNS stem cell research signaling oncology epigenetic research receptors Ion channels Biomarkers labeling reagent transcription factors ligand sets proteins screening library