NHS-PEG-NHS [10066/HO023023][CAS no. -]_Biochempeg Scientific/Biopharma PEG - 코아사이언스

 

NHS-PEG-NHS

Cat.#	M.W.	Unit
HO023023-1K	1K	1g, 5g
HO023023-2K	2K	1g, 5g
HO023023-3.4K	3.5K	1g, 5g
HO023023-4K	4K	1g, 5g
HO023023-5K	5K	1g, 5g
HO023023-6K	6K	1g, 5g
HO023023-8K	8K	1g, 5g
HO023023-10K	10K	1g, 5g
HO023023-20K	20K	1g, 5g
HO023023-40K	40K	1g, 5g

• Synonyms：SC-PEG-SC, Succinimidyl ester-PEG-Succinimidyl ester
• Recommended Storage Condition：
• Uses：

NHS-PEG-NHS is an amino (-NH2) reactive PEG derivative, which can be used to modify proteins, peptides or any other surface.

The NHS ester reacts with the primary amine group of pH 7~8.5 to form a stable amide bond. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to alkaline pH to proceed. Primary amines react with NHS esters through nucleophilic attack, and NHS is released as a by-product. The competition between the hydrolysis of NHS-ester and the reaction in the aqueous solution increases with the increase of pH.

Compared with other PEG NHS ester derivatives, the succinimide carbonate (SC) functionalized mPEG-NHS of NHS-PEG-NHS provides excellent reactivity and higher stability in aqueous solutions.

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코아사이언스 coresciences Biochempeg Scientific Inc.USA Korea distributor 한국 대리점 Biochempeg,  founded in 2013,  is a biotechnology-oriented company in Watertown, Massachusetts. We are dedicated to manufacturing and supplying high purity polyethylene glycol (PEG) derivatives and linkers, monodisperse PEG, ADC PEG linkers, Click Chemistry reagents,  PEGylation services and custom PEG derivative synthesis to clients worldwide. These PEG linkers have been widely used in bioconjugation, antibody-drug conjugates (ADCs) therapeutic, drug delivery and diagnostics field Biopharma PEG