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[사람/인간 핵내수용체/핵 수용체 단클론 항체] Monoclonal Antibodies to 48 Human Nuclear Receptors_Funakoshi - 코아사이언스

코피디 2017. 7. 21. 16:38

Monoclonal Antibodies to 48 Human Nuclear Receptors

 

Nuclear hormone receptors are a family of 48 intracellular receptors. Lipid-soluble ligand bound receptors

move to the nucleus to function as transcriptional activators, associating with other general transcription factors.

This regulates gene ｅxpression relates to various metabolic pathways.

Malfunctions in nuclear hormone receptor signaling pathways caused by an individuals' habits leads

to a variety of life-style related diseases, such as type II diabetes, obesity, hyperlipidemia, and

circulatory disorders.

 

Perseus Proteomics Inc.'s mouse monoclonal antibodies have high affinity and specificity for nuclear receptors.

All antibodies are validated by the reactivity with the proteins from full length cDNA expressed in mammalian cells. 

 

Features 

・ Raised in Perseus Proteomics Inc.

・ Validated by full length proteins

・ Application : ELISA and Western Blot.

   Some antibodies can be used for immunohistochemistry (IHC).

・ Reactivity : Human (Some antibodies crossreact with rat or mouse) 

 

■ Androgen Receptor

 

#PP-H7507-00 Anti-Androgen Receptor, Human, Mouse-Mono(H7507) <Anti-AR>

 

Human Prostate Gland (Paraffin Section)

 

■ Estrogen Receptor

 

#PP-H4624-00 Anti-Estrogen Receptor α, Human, Mouse-Mono(H4624) <Anti-ERα>

 

Human Uterus Endometrial Epithelium (Paraffin Section)

 

#PP-H5844-00 Anti-Estrogen-Related Receptor α, Human, Mouse-Mono(H5844) <Anti-ERRα>

 

Human Heart Myocardium (Paraffin Section)

 

 

Products 

 

Target Cat.# Immunogen Cross-
reactivity		 Application Size Storage
Androgen Receptor (AR) PP-H7507-00 Human M,  R E, WB, IP, IHC 100μl -20℃
Constitutive Androstane Receptor (CAR) PP-N4111-00 Human M,  R E, WB, NW, IP  IHC
Chicken ovalbumin upstream promotor transcription factor 1 (COUP-TFI) PP-H8132-00 Human M,  R E, WB, IP, IHC
PP-H8124-00 Human M,  R E, WB, NW, IHC
Chicken ovalbumin upstream promoter transcription factor 2 (COUP-TFII) PP-H7147-00 Human M,  R E, WB, IP, IHC
DSS-AHC critical region on the X chromosome, gene1 (DAX1) PP-H7431-00 Human 　 E, WB
V-erbA related orphan nuclear receptor (EAR2) PP-N2025-00 Human R E, WB, NW, IP, IHC
PP-H9929A-00 Human M,  R E, WB, NW, IHC
Estrogen Receptor alpha (ER alpha) PP-H4624-00 Human M,  R E, WB, IP, IHC
Estrogen Receptor beta (ER beta) PP-PPZ0506-00 Human 　 E, WB, IP
Estrogen-Related Receptor alpha (ERR alpha) PP-H5844-00 Human M,  R E, WB, NW, IP, IHC
Estrogen-Related Receptor beta (ERR beta) PP-H6705-00 Human M,  R E, WB, NW, IP, IHC
PP-H6707-00 Human 　 E, WB, NW, IP
Estrogen-Related Receptor gamma(ERR gamma) PP-H6812-00 Human M,  R E, WB, IP  IHC
Farnesoid X-activated receptor (FXR) PP-A9033A-00 Human M,  R E, WB, IP, IHC
Germ Cell Nuclear Factor (GCNF) PP-H7921-00 Human 　 WB, NW, IP
Glucocorticoid Receptor, Common (GR) PP-H8031-00 Human M,  R E, WB, IP, IHC
Glucocorticoid Receptor, Common (GR) PP-H8004-00 Human R E, WB, IP, IHC
Hepatocyte nuclear factor 4-alpha (HNF4 alpha) PP-H1415-00 Human M,  R E, WB, NW, S, IP, IHC, ChIP
PP-K9218-00 Human M,  R E, WB, S, IP, IHC
Hepatocyte nuclear factor 4-alpha (HNF4 alpha7) PP-H6939-00 Human M,  R E, WB, NW, IP  IHC
Hepatocyte nuclear factor 4-gamma (HNF4) PP-B6502A-00 Human R E, WB, NW, IP  IHC
PP-N3224-00 Human M,  R E, WB, NW, IHC
Liver Receptor Homologue 1 (LRH-1) PP-H2325-00 Human M,  R E, WB, IP
PP-K8801-00 Human 　 E, WB, IP
Liver X Receptor alpha (LXR alpha) Ligand Binding Domain PP-PPZ0412-00 Human M,  R E, WB, S, IP, IHC  ChIP
Liver X Receptor alpha (LXR alpha) PP-K8607-00 Human 　 E, WB, S, IP, ChIP
Liver X Receptor beta (LXR beta) PP-K8917-00 Human 　 E, WB, NW, IP
Mineralocorticoid Receptor (MR) PP-H3122-00 Human M,  R E, WB, IP, IHC
Nerve growth factor-induced clone B alpha (NGFI-B alpha) PP-H1648-00 Human 　 E, WB, IP
Nerve growth factor-induced clone B beta (NGFI-B beta) PP-N1404-00 Human M,  R E, WB, NW, IP, IHC
Nerve growth factor-induced clone B gamma (NGFI-B gamma) PP-H7833-00 Human 　 E, WB, IP
Photoreceptor-specific Nuclear Receptor (PNR) PP-H7223-00 Human R E, WB, IHC
Peroxisome Proliferator-Activated Receptoralpha (PPAR alpha) PP-H0723-00 Human M E, WB, S, IP, ChIP
Peroxisome Proliferator-Activated Receptor gamma (PPAR gamma, Common) PP-A3409A-00 Human M,  R E, WB, S, IP, IHC, ChIP
PP-K8713-00 Human M E, WB, S, IP, ChIP
Peroxisome Proliferator-Activated Receptor gamma2 (PPAR gamma2) PP-K8450B-00 Human M E, WB, NW, S
Peroxisome Proliferator-Activated Receptor delta (PPAR delta) PP-K9436-00 Human 　 E, WB, S
Progesterone Receptor, Common (PR) PP-A9621A-00 Human M,  R E, WB, NW, IP, IHC
Progesterone Receptor, Isoform B (PR) PP-H5344-00 Human M,  R E, WB, NW, IP, IHC
Pregnane X receptor (PXR, Common) PP-H4417-00 Human 　 E, WB, NW, IP
Pregnane X receptor (PXR-2) PP-H0502-00 Human 　 E, WB, NW
Pregnane X receptor alpha (RAR alpha) PP-H1920-00 Human 　 E, WB, NW, IP
Pregnane X receptor beta (RAR beta) PP-H4338-00 Human 　 E, WB, IP
Pregnane X receptor gamma (RAR gamma) PP-H5620-00 Human 　 E, WB, IP
Rev-erb alpha (REVERB alpha) PP-A8740A-00 Human 　 E, WB, NW, IP
Rev-erb alpha (REVERB beta) PP-H2729-00 Human R E, WB, IP, IHC
RAR-related orphan receptor (ROR), Common PP-H3925-00 Human M,  R E, WB, IP  IHC
RAR-related orphan receptor alpha (ROR alpha) PP-H3910-00 Human 　 E, WB, IP
RAR-related orphan receptor beta (ROR beta) PP-N7927-00 Human 　 E, WB, NW
RAR-related orphan receptor gamma (ROR gamma) PP-H6437-00 Human 　 E, WB, IP
Retinoid X Receptor alpha (RXR alpha) PP-K8508-00 Human M,  R E, WB, S, IP, IHC, ChIP
Retinoid X Receptor beta (RXR beta) PP-H7341-00 Human R E, WB, NW, IP
Retinoid X Receptor gamma (RXR gamma) PP-H3210-00 Human 　 E, WB, NW, IP
Small heterodimer partner (SHP) PP-N7519-00 Human 　 E, WB, NW
Steroidogenic Factor 1 (SF-1) PP-N1665-00 Human M,  R E, WB, NW, IP, IHC
Tailless homologue (TLX) PP-H6506-00 Human 　 E, WB, IP
PP-H6510-00 Human M,  R E, WB, IP, IHC
Tasticular receptor 2 (TR2) PP-H0037-00 Human 　 E, WB, IP
Tasticular receptor 4 (TR4) PP-H0107B-00 Human M,  R E, WB, IP, IHC
Thyroid Hormone Receptor alpha (TR alpha) PP-H2804-00 Human M,  R E, WB, NW, IHC
Thyroid Hormone Receptor beta1 (TR beta1) PP-H3825A-00 Human 　 E, WB, IP
Vitamin D Receptor (VDR) PP-H4537-00 Human M,  R E, WB, IP, IHC

* Cross-reactivity ; M = Mouse, R = Rat

* Applications ;  

E: ELISA , WB: Western Blotting,  NW: Non-Reducing Western Blotting, S: Super Shift Assay, 

IP: Immunoprecipitaion, IHC:  Immunohistochemistory,  ChIP: Chromatin Immunoprecipitation

 

* NOTICE : FOR RESEARCH USE onLY. NOT FOR DIAGNOSTIC USE.

 

 

coresciences 코아사이언스 funakoshi  bioacademia 항체 한국 대리점 모노클로날 안티바디 항체 핵수용체 유전자전사 gene transcription 대사 metabolism 항상성 homeostasis 글루코코이드수용체 glucocoid receptor 인트로겐수용체 androgen receptor 에스트로겐수용체 estrogen receptor 세포핵내 DNA전사 조절 수용체 리셉터 배위자 ligand 전사인자  Perseus Proteomics Inc.

 

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