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IPP-14

Cat.# DC70514 / Size: 100mg, 250mg, 1g

IPP-14 is a novel PAK1 inhibitor that selectively blocks the PAK1-PUMA binding and suppresses cell proliferation via PUMA-dependent manner; suppresses cancer cell viability and migration, induces p21 expression and induces M-phase arrest by inhibition of PAK1; also induces p21/WAF1/CIP1 (Cyclin-dependent kinase inhibitor 1A) expression by releasing from Bcl-2 and by inhibition of AKT-mediated p21 suppression.

Chemical Properties 

Cas No.:
Chemical Name:
IPP-14
Synonyms:
IPP14
Formula:
C24H28N4O4S
M.Wt:
468.572
Sotrage:
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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코아사이언스 coresciences DC Chemicals Korea 한국 대리점