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What is Parkinson's disease Parkinson's disease (PD) is a neurodegenerative disease. It is caused by the rapid structural degeneration of the substantia nigra in the brain and the inability to produce the neurotransmitter "dopamine", which limits the brain's ability to direct movement. Greatly hinders the patient's ability to move; the main clinical features of PD are bradykinesia accompanied by..
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Introduction Cytokine (CK) is a type of small molecule protein with a wide range of biological activities. It is composed of immune cells (such as monocytes, macrophages, T cells, B cells, NK cells, etc.) and some non-immune cells. (Endothelial cells, epidermal cells, fibroblasts, etc.) are synthesized and secreted upon stimulation. Cytokines bind to their target cells through receptors on the c..
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Vascular endothelial growth factor (VEGF) is a type of highly biologically active glycoprotein. In 1989, Ferrara et al. purified VEGF from beef wattle and found that it was an endothelial cell-specific mitogen. Its amino acid sequence was similar to that of known proteins at that time. The amino acid sequences are all different. According to its activity in promoting mitosis of vascular endothel..
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4 unique monoclonal antibodies for cancer-related anti-lamininUseful monoclonal antibodies for the research of cancer pathologyLaminins are major extracellular matrix proteins containing over 15 members. Laminins are large hetero-trimers consisting of 5 alpha chains, 3 beta chains, and 3 gamma chains. Due to its structural varieties, it has been challenging to detect each laminin isoform by conv..
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New Products mGluR1: glutamate receptors involved in motor learning and long-term depression mGluR1 (also termed Grm1) is a G protein-coupled receptor (GPCR) that exists in four isoforms (mGluR1α, β, γ, δ), which can occur as homodimers or heterodimers. In neuronal cell types the alpha1 isoform is mainly expressed in cerebellar Purkinje cells, and also in neurons of the striatum and the in the o..
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How can inflammatory processes be fine-tuned? Two new antibodies against Arginase-1, a metabolic enzyme with a newly discovered role in inflammatory control The immune system is the body's defense against pathological external and internal attacks. However, this powerful system must be strictly regulated, since an excessive inflammatory reaction could have serious and even lethal consequences.Ni..
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Horse Cor(Cortisol) ELISA KitCat. # ELK8554 / Size: 48T, 96T OverviewProduct name:Horse Cor(Cortisol) ELISA KitReactivity:HorseAlternative Names:HydrocortisoneAssay Type:Competitive InhibitionSensitivity:0.97 ng/mLStandard:200 ng/mLRange:3.13-200 ng/mLSample Type:serum, plasma, urine and other biological fluidsAssay Length:2hResearch Area:Metabolic pathway;Endocrinology;Hormone metabolism;Test p..
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mCherry-Tag Mouse pAb Cat. # EA012 / Size: 50uL, 100uL Overview Product name: mCherry-Tag Mouse pAb Source: Mouse Dilutions: WB 1:5,000 IF 1:200 IHC 1:200 IP 1:100 Immunogen: Recombinant Protein Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. Clonality: Polyclonal Isotype: IgG Concentration: 1mg/mL Background: mCherry is a fluoroph..
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