Demethylsuberosin; 7-demethylsuberosin [T5774][CAS no. 21422-04-8]_TargetMol - 코아사이언스

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Demethylsuberosin

Cat.# T5774 / Size: 20mg, 1 mL * 10 mM (in DMSO)

7-demethylsuberosin is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory effects on PGE2 production with the IC50 values of 9.42 μM.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Chemical Properties 

Synonyms	7-demethylsuberosin
Molecular Weight	230.263
Formula	C14H14O3
CAS No.	21422-04-8

Storage & Solubility 

Storage

Powder: -20°C for 3 years In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )

References & Literature 

1. Kim HJ, Kim HM, Ryu B,et al.Constituents of PG201 (Layla(®)), a multi-component phytopharmaceutical, with inhibitory activity on LPS-induced nitric oxide and prostaglandin E2 productions in macrophages[J].Arch Pharm Res. 2016 Feb;39(2):231-239.

2. Lacroix D , Prado S , Kamoga D , et al. Structure and in Vitro Antiparasitic Activity of Constituents of Citropsis articulata Root Bark[J]. Journal of Natural Products, 2011, 74(10):2286-2289.

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