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Cleavable & Non-Cleavable PEG Linkers for XDCs_Biopharma PEG Scientific Inc. - 코아사이언스

코피디 2023. 3. 17. 15:50

안녕하세요!

PEG 및 PEG derivatives 합성 전문 제조사 Biopharma PEG Scientific Inc. 한국 대리점 코아사이언스 입니다.

관련 상품 견적 및 문의, 주문은 info@coresciences.co.kr로 연락주시기 바랍니다.

Linker chemistry determines the stability of the drug conjugates (ADCs / PDCs) and the payload release rate. There are currently two main types of linker chemistry: cleavable and non-cleavable.

  • Cleavable linkers contain a trigger that can release the cytotoxic agent after internalization. Cleavable linkers may also help with destroying cancer cells adjacent to their targets through a process referred to as "bystander effect".
  • Non-cleavable linkers rely on the degradation of the antibody itself to release the drug-linker.

Biopharma PEG provides large-scale GMP manufacture of high-purity PEG linkers for your XDCs research and development. 

Non-Cleavable PEG Linkers

Cleavable PEG Linkers

* 본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

 

코아사이언스 coresciences Biochempeg Scientific Inc.USA Korea distributor 한국 대리점 Biochempeg,  founded in 2013,  is a biotechnology-oriented company in Watertown, Massachusetts. We are dedicated to manufacturing and supplying high purity polyethylene glycol (PEG) derivatives and linkers, monodisperse PEG, ADC PEG linkers, Click Chemistry reagents,  PEGylation services and custom PEG derivative synthesis to clients worldwide. These PEG linkers have been widely used in bioconjugation, antibody-drug conjugates (ADCs) therapeutic, drug delivery and diagnostics field Biopharma PEG

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