티스토리 뷰

 

Spinosin

=6-(2-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one

Cat.# CFN99600 / Size: 20mg      

Cas No.: 72063-39-9

Purity: > 98%

C28H32O15 608.55

Physical Description:  Yellow powder

 

Manual    COA    MSDS  

 

Source ]

The seeds of Zizyphus jujuba

 

Biological Activity ]

Spinosin has neuroprotective, anxiolytic-like and anti-inflammatory effects, it ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, it also potentiated pentobarbital-induced sleep via the serotonergic system.

 

[Solvent]

DMSO, Pyridine, Methanol, Ethanol, etc.

 

[Storage]

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8°C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

 

[After receiving]

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

 

[References]

1. Biomol Ther (Seoul). 2015 Mar;23(2):156-64. Spinosin, a C-Glucosylflavone, from Zizyphus jujuba var. spinosa Ameliorates Aβ1-42 Oligomer-Induced Memory Impairment in Mice.[Pubmed:25767684]

2. Pharmacol Biochem Behav. 2015 Jan;128:41-9. GABA and 5-HT systems are implicated in the anxiolytic-like effect of spinosin in mice.[Pubmed: 25449359]

3. Pharmacol Biochem Behav. 2014 May;120:88-94. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice.[Pubmed: 24582850]

4. J Chromatogr Sci. 2015 Jan;53(1):97-103. Brain tissue distribution of spinosin in rats determined by a new high-performance liquid chromatography-electrospray ionization-mass/mass spectrometry method.[Pubmed: 24771055]

 

코아사이언스 coresciences wuhan chemfaces korea biochemical high quality phytochemicals reference standards analytical standard natural active ingredients products 표준품 기능성분 표준물질 지표성분 주성분 유효성분 순품

Ziziphus jujuba var. spinosa (Bunge) Hu 산조인 산조 백극 jujube 갈매나무과 대추씨 종자 신경안정 수면유도 작용 멧대추  Ziziphus spp. Ziziphus jujuba var.spinosa Ziziphus jujuba Iris nertshinskia Clutia abyssinica Swertia spp. Strophioblachia fimbricalyx Boerlrpinolene