티스토리 뷰

Bakuchiol

=4-[(1E,3S)-3-ethenyl-3,7-dimethylocta-1,6-dienyl]phenol

Cat.# CFN99047 / Size: 20mg

Cas No.: 10309-37-2

Purity: > 98%

C18H24O 256.4

Physical Description: Oil

Manual    COA    MSDS

 

[ Source ]

The bark of Psoralea corylifolia

 

Biological Activity ]

Bakuchiol possesses anti-tumor, cytotoxic, anti-bacterial , and anti-helmenthic properties, it shows DNA polymerase1 inhibiting activity. Bakuchiol has great potential for use in food additives and mouthwash for preventing and treating dental caries.

 

[ Solvent ]

Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.

 

[Storage]

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8°C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

 

[After receiving]

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

 

[ References ]

1. Chem. Res. Toxicol., 2003, 16(9), 1062-1069.

2. Antimicrob Agents Chemother., 2001, 45(11), 3009-3013.

3. J. Ethnopharmacology, 1999, 68, 295.

4. J. Nat. Prod., 1998, 61, 362.

5. Zhong Yao Cai. 2014 Apr;37(4):632-5. Regulative effect of bakuchiol on ESF-1 cells anti-aging gene[Pubmed: 25345139]

6. Phytomedicine. 2014 Jun 15;21(7):942-5. Anti-dermatophytic activity of bakuchiol: in vitro mechanistic studies and in vivo tinea pedis-inhibiting activity in a guinea pig model.[Pubmed:24703327]

7. Pharmazie. 2014 Jan;69(1):60-3. Inhibition potential of UDP-glucuronosyltransferases (Ugts) 1A isoforms by the analogue of resveratrol, bakuchiol.[Pubmed: 24601226]

8. Eur J Med Chem. 2012 Mar;49:55-67. Bakuchiol derivatives as novel and potent cytotoxic agents: a report.[Pubmed: 22245048]

9. Yao Xue Xue Bao. 2010 Apr;45(4):467-70. Vitro antitumor activity and synthesis of the key intermediate of bakuchiol.[Pubmed: 21355211]

 

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