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실험.연구용 추천상품

[Newsletter] 2026년 6월 New Compounds_TargetMol - (주) 코아사이언스

코피디 2026. 6. 18. 12:32

안녕하세요!

TargetMol (Target molecule Corp.) 공식 수입/공급 업체 코아사이언스 입니다.

 

자세한 상품 정보 및 관련 문의는 전화 02-858-0328 또는 info@coresciences.co.kr로 문의주시기 바랍니다.

감사합니다!

SIJ1777

SIJ1777 is a pyrimidopyrimidinone class type II pan-BRAF inhibitor, optimized as a derivative of GNF-7. It exerts anti-tumor effects by simultaneously inhibiting the phosphorylation and activation of the MAPK pathway (MEK/ERK) and the PI3K/AKT pathway.  

 

Research Areas: Cancer

Targets:  MEK; ERK; Akt; Apoptosis

 

MSU-44147

MSU-44147 is a small-molecule inhibitor that targets the membrane transport protein MmpL3 in Mycobacterium abscessus. MSU-44147 exhibits selective anti-mycobacterial activity and low cytotoxicity toward eukaryotic cells. 

 

Research Areas: Infection

Targets:  Bacterial

 

LN-439A

LN-439A is a novel tetrahydro-β-carboline small molecule that acts as a potent catalytic inhibitor of the BAP1 deubiquitinase. It induces ubiquitination and degradation of the KLF5 transcription factor by binding to the catalytic pocket of BAP1. 

 

Research Areas: Cancer

Targets:  KLF; RAD51

 

LLS30

LLS30 is an allosteric inhibitor of Galectin-1 (Gal-1). LLS30 inhibits the downstream MEK/ERK signaling pathway and also inhibits Akt phosphorylation. LLS30 exhibits potent proliferation-inhibitory activity against various prostate cancer cell lines.

 

Research Areas: Cancer

Targets:  MEK; ERK

 

LG-121071

LG-121071 is an orally active selective androgen receptor modulator (SARM) with a Ki of approximately 17 nM for the androgen receptor. It is commonly used in studies of androgen receptor-related diseases, such as prostate cancer.

 

Research Areas: Cancer

Targets:  Androgen Receptor

 

IA65

IA65 is a selective small molecule agonist that enhances Orai1 channel-mediated calcium influx and activates calcium-dependent inactivation mechanisms. 

 

Research Areas: Cardiovascular Research

Targets: Orai1 agonist

 

Frevecitinibum

Frevecitinibum is a Janus kinase (JAK) inhibitor with activity against multiple JAK isoforms, including JAK1, JAK2, JAK3, and TYK2, thereby suppressing activation of the JAK-STAT signaling pathway. 

 

Research Areas: Immunology & Inflammation

Targets: JAK/Pan-JAK

 

* 본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

코아사이언스 coresciences Target molecule Corp TargetMol USA distributor Korea 한국 대리점

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