[Magic Building Blocks Series 18] Imidazo[1,2-b]pyridazine building blocks_ChemScene - 코아사이언스

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Introduction

Imidazo[1,2-b]pyridazine, a bicyclic heteroaromatic structure formed by fusing imidazole and pyridazine rings, has emerged as a valuable scaffold in drug discovery. The planar, nitrogen-rich architecture provides multiple hydrogen-bonding sites, enabling strong interactions with diverse biological targets. Its inherent rigidity minimizes conformational flexibility, enhancing binding selectivity and reducing off-target effects. Moreover, this scaffold can be easily functionalized at various positions, enabling fine-tuning of its pharmacological properties for diverse therapeutic applications. So far, Chemscene has developed many imidazo[1,2-b]pyridazine building blocks.

Imidazo[1,2-b]pyridazine building blocks

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Latest Publications Citing Use of ChemScene Products

Small 2407549, (2025).
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