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Monocarboxymethylene Blue NHS ester (MCMB-SE)

Cat.# AF-0202-D005.0-001 / Size: 5mg

Cat.# AF-0202-D020.0-001 / Size: 20mg

Cat.# AF-0202-D050.0-001 / Size: 50mg

Amine-reactive methylene blue redox marker for electro-active labeling, designed especially for labeling of biomolecules.

Properties

Molecular Weight:
538,96
Empirical Formula:
C22H23N4O8SCl
Absorption [nm]:
665 ± 3
Emission [nm]:
670 ± 3
ε [M-1 cm-1]:
>81 000
Solubility:
Acetonitrile
Appearance (colour):
dark blue
Appearance (form):
solid (powder)
Storage:
- 20 °C. Keep dry! Keep away from light, especially in solution!
Trade name:
Monocarboxymethylene blue succinimidyl ester; Monocarboxymethylene blue NHS ester; Methylene blue NHS ester; Methylene blue succinimidyl ester
Reactive Moiety:
NHS ester, reacts with 1° amines to form a stable amide linkage

Description

The amine-reactive methylene blue derivative is used as an electroactive labeling reagent for covalent attachment to proteins and alkylamino modified nucleic acids. Monocarboxymethylene blue contains a single activated carboxylic acid functional group. In addition to its relatively high absorption, MCMB, has excellent and validated redox properties and is a good generator for singlet oxygen, making it to a particularly suitable label for electrochemical and photosensitzer applications.

MCMB-SE

CAS: none known

*Absorption and fluorescence emission maxima of monocarboxymethylene blue (MCMB, F-0202) in TE buffer pH 7.6

Formal Electrode Potential vs. Ag/AgCl (1 M KCl): Ef = -0.198 V

* 본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.

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