[알로에 표준물질][Flavonoids] Aloesin (알로에신) [CFN91659][CAS no. 30861-27-9]_ChemFaces - 코아사이언스

 

Aloesin

Cat.# CFN91659 / Size: 20mg

CAS No.:	30861-27-9
Catalog No.:	CFN91659
Molecular Formula:	C19H22O9
Molecular Weight:	394.37 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Aloe arborescens Mill.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)

[ Biological Activity ]

Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, inhibits tyrosinase (IC50 = 0.9 mM)activity and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway

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[Storage]

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8°C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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[After receiving]

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

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[ References ]

1. Anal Cell Pathol (Amst) . 2017;2017:8158254. Aloesin Suppresses Cell Growth and Metastasis in Ovarian Cancer SKOV3 Cells through the Inhibition of the MAPK Signaling Pathway[Pubmed: 28702312]

2. Phytomedicine . 2017 May 15;28:19-26. Aloesin from Aloe vera accelerates skin wound healing by modulating MAPK/Rho and Smad signaling pathways in vitro and in vivo[Pubmed: 28478809]

3. Clin Exp Dermatol . 2002 Sep;27(6):513-515. Aloesin inhibits hyperpigmentation induced by UV radiation[Pubmed: 12372097]

4. Regul Toxicol Pharmacol . 2011 Nov;61(2):215-221. In vitro and in vivo assessment of the genotoxic activity of aloesin[Pubmed: 21821088]

5. Biochem Mol Biol Int . 1997 Feb;41(2):285-292. Aloesin up-regulates cyclin E/CDK2 kinase activity via inducing the protein levels of cyclin E, CDK2, and CDC25A in SK-HEP-1 cells[Pubmed: 9063568]

6. Fitoterapia . 2021 Apr;150:104828. Anti-tyrosinase activity of South African Aloe species and isolated compounds plicataloside and aloesin[Pubmed: 33434632]

7. Phytomedicine . 2017 May 15;28:19-26. Aloesin from Aloe vera accelerates skin wound healing by modulating MAPK/Rho and Smad signaling pathways in vitro and in vivo[Pubmed: 28478809]

8. Regul Toxicol Pharmacol . 2011 Nov;61(2):215-221. In vitro and in vivo assessment of the genotoxic activity of aloesin[Pubmed: 21821088]

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관련 상품

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