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N1-MethylpseudoUridine-5'-Triphosphate Sodium

Cat.# B2706-358101 / Size: 1mL

 

It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA.

The product has passed the functionality test in transcription reaction. The solution is free of DNase and RNase contamination.

Category: Carbohydrates, Nucleosides & Nucleotides

Structure/Application: Nucleotides applied on DNA/RNA

Molecular Formula: C10H17N2O15P3.xNa

Molecular Weight: 498.17 (free acid)

Purity: 99%, 100mM sodium salt solution

Related CAS: 1931922-77-8 (tetrasodium salt) 1428903-59-6 (free acid)

Appearance: Colourless to slightly yellow liquid

Synonyms: N1-Me-pUTP Sodium salt; 1-Methylpseudouridine-5'-Triphosphate sodium salt; N1-Methylpseudo-UTP sodium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-, sodium salt; 1-Methylpseudo-UTP sodium salt; N1-methyl-pseudouridine 5'-triphosphate, sodium salt

IUPAC Name: sodium salt;[[(2R,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Solubility: Soluble in Water

Storage: Store at -20 °C

 

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