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GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) [4030663/H-6795][CAS no. 107444-51-9]_Bachem - 코아사이언스
코피디 2024. 5. 31. 15:46GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)
Product # 4030663 / Size: 0.5mg, 1g
PRODUCT DESCRIPTION
GLP-1 (7-36) amide is secreted from the lower small intestine and shows a strong insulinotropic effect. GLP-1 (7-36) amide is considered as the most important incretin hormone. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells. Considerable interest has focused on the development of this peptide as a therapeutic strategy for non-insulin-dependent (type 2 ) diabetes mellitus and associated neuropathy.
Salt form: Trifluoroacetate
Molecular weight: 3297.68
Chemical Formula: C₁₄₉H₂₂₆N₄₀O₄₅
Storage Temperature: < -15°C
Synonyms: Preproglucagon (98-127) amide (human, bovine, guinea pig, mouse, rat)
One Letter code: HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH₂
Source: Synthetic
Old Product Number: H-6795
Literatures
Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts
C.-H.Chang et al., Molecules, 19, 19066 (2014)
L.Brunetti et al., Peptides, 29, 1377 (2008)
C.Orskov and J.H.Nielsen, FEBS Lett., 229, 175 (1988)
Glucagon-like peptide 1 (GLP-1) as a new therapeutic approach for type 2-diabetes.
M.A.Nauck et al., Exp. Clin. Endocrinol. Diabetes, 105, 187 (1997)
Effects of glucagon-like peptide-1(7-36)amide on the concentrations of insulin and glucose in sheep.
P.A.Martin and A.Faulkner, Comp. Biochem. Physiol. Comp. Physiol., 105, 705 (1993)
Exon duplication and divergence in the human preproglucagon gene.
G.I.Bell et al., Nature, 304, 368 (1983)
Glucagon-like peptide-1 7-36: a physiological incretin in man.
B.Kreymann et al., Lancet, 2, 1300 (1987)
L.Brunetti et al., Peptides, 29, 1377 (2008)
J.-P.Raufman et al., J. Biol. Chem., 267, 21432 (1992)
The glucagon-like peptides: a double-edged therapeutic sword?
T.Perry and N.H.Greig, Trends Pharmacol. Sci., 24, 377 (2003)
J.J.Meier et al., Biodrugs, 17, 93 (2003)
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