[마늘 표준물질] Alliin (알리인; 알린) [CFN93533][Cas No. 556-27-4]_Chemfaces 한국대리점 - 코아사이언스

 

Alliin

Cat.# CFN93533 / Size: 20mg

CAS No.:	556-27-4
Catalog No.:	CFN93533
Molecular Formula:	C6H11NO3S
Molecular Weight:	177.22 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The bulbs of Allium sativum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF

[Biological Activity]

Alliin has antiglycating potential , it offers protection against glucose or methyglyoxal induced glycation of superoxide dismutase, hence is expected to have therapeutic potential in the prevention of glycation-mediated diabetic complications. Alliin has anti-inflammatory activity, it protects against Lipopolysaccharides (LPS)-induced acute lung injury (ALI) by activating PPARγ, which subsequently inhibits LPS-induced NF-κB activation and inflammatory response; alliin has an inhibitory effect in osteoclasteogenesis with a dose-dependent manner via blocking the c-Fos-NFATc1 signaling pathway, it could be a potential therapeutic agent in the treatment of osteoporosis. Alliin and sabinene have detectable levels of antimicrobial activity.

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[Storage]

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8°C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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[After receiving]

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

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[References]

1. Int J Mol Sci. 2016 Sep 20;17(9). pii: E1516. Alliin Attenuated RANKL-Induced Osteoclastogenesis by Scavenging Reactive Oxygen Species through Inhibiting Nox1.[Pubmed: 27657047]

2. J Ethnopharmacol. 2017 May 5;203:171-181. Antibacterial activity of medicinal plants from The Physicians of Myddvai, a 14th century Welsh medical manuscript.[Pubmed: 28344030 ]

3. Microb Pathog. 2017 Jul 12;110:375-379. Effects of alliin on LPS-induced acute lung injury by activating PPAR[Pubmed: 28711511]

4. Int J Biol Macromol. 2017 Oct;103:182-193. Inhibitory effect of alliin from Allium sativum on the glycation of superoxide dismutase.[Pubmed: 28502851]

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관련 상품

한방/생약 지표성분, 표준품, 표준물질, 유효성분, 기능성분

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