Click Chemistry Reagents_BroadPharm - 코아사이언스

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PEG Linkers, Click Chemistry Tools, ADC Linkers, PROTAC Linkers, Drug Delivery Lipids, Nucleoside, Phosphoramidite, Labeling Reagents 전문 제조사 BroadPharm 한국 대리점 코아사이언스 입니다.

 

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Click Chemistry Reagents

Click Chemistry is a chemical reaction between pairs of reagents (named click chemistry tools) to exclusively react with each other under mild condition and is effectively inert to naturally occurring functional groups such as the amine group.

Click Chemistry has been widely used in bioconjugation, biolabeling and material sciences in pharmaceutical and biotech industry due to its mild conditions and high selectivity. Click Chemistry reactions can be categorized into three categories:

• (1) Cu(I)-catalyzed Azide-Alkyne Click Chemistry reaction (CuAAC);
• (2) Strain-promoted Azide-Alkyne Click Chemistry reaction (SPAAC). It is biocompatible.
• (3) Ligation between tetrazine and alkene (trans-Cyclooctene). This high-speed reaction is also copper free which is ideal for in vivo cell labeling.

BroadPharm provides over 500 high purity Click Chemistry tools (reagents or kits) with a broad range of functional groups: Azide, Alkyne, DBCO, TCO, Tetrazine, BCN...

• Alkyne

  Alkyne reagents can be reacted with azide-bearing compounds or biomolecules via Cu-catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.... Click to read more.

  

   

• Azide

  Azide click chemistry is a very popular chemistry that is widely used in pharmaceutical and biotech field due to its mild condition, fast speed and biocompatibility. The 1st generation of azide click chemistry is enabled through the reaction of Azid... Click to read more.

  

   

   

• BCN

  BCN reagent is a class of click chemistry reagents containing a very reactive BCN (bicyclo[6.1.0]nonyne) group, BCN reagents can react with azide-tagged molecules or biomolecules via copper-free Click Chemistry. It can be run either in aqueous buffer... Click to read more.

  

   

   

• Click Reaction Ligands

  The efficiency of a copper (Cu(I))-catalyzed Azide-Alkyne click chemistry reaction (CuAAC) strongly depends on the presence of copper ions Cu(+I). Copper(I) ions are easily oxidized and undergo disproportionation, also has cytotoxic effects to liv... Click to read more.

  

   

   

• DBCO

  DBCO reagent is a class of click chemistry labeling reagents containing a very reactive DBCO ((Dibenzocyclooctyne) group, DBCO reagent can react with azide-tagged molecules or biomolecules via copper-free Click Chemistry. DBCO click chemistry can be... Click to read more.

  

   

   

• TCO

  TCO click chemistry is the 3rd generation click chemistry that is widely used in labeling and bioconjugation due to its fast speed and biocompatibility. It is the reaction between TCO (trans-cycloctene) reagent and Tetrazine moiety in an inverse elec... Click to read more.

  

   

   

• Tetrazine

  Tetrazine reagents is a class of click chemistry labeling reagents containing a reactive tetrazine group, Tetrazine reagent is highly reactive with TCO (trans-cycloctene) in an inverse electron demand Diels Alder reaction followed by a retro-Diels Al... Click to read more.

   

 

 

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코아사이언스 coresciences BroadPharm Korea distributor 한국 대리점 high purity PEG linkers Click chemistry reagents drug delivery Lipids & advanced labeling reagents Dye Labeling & Biotin Labeling compounds PEG Linkers ADC Linkers Click Chemistry Reagents Polymer PEG, Copolymer PROTAC Lipids In Drug Delivery Nucleoside, Nucleotide, Phosphoramidite Fluorescent Dye Biotinylation reagents Dye Antibody Labeling Kit Biotin Antibody Labeling Kit Protein Crosslinking Kit Enzyme, Antibody, Substrate