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Cardanol monoene

Cat.# B2693-292204 / Size: 5mg

Cardanol monoene is also known as anacardic acid (C15:1). It inhibits the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 with an IC50 of 6.8 mM. Cardanol monoene is also a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 µM in vitro. It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 µM after 24 and 48 hours of treatment, respectively). A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation.

CAS no. 501-26-8

Category: Inhibitor

Targets: Lipoxygenases (LOXs)

Molecular Formula: C21H34O

Molecular Weight: 302.5

Appearance: Neat Oil

Synonyms: Cardanol C15:1; 6[8'(Z)-pentadecenyl]salicylic acid

InChI Key: YLKVIMNNMLKUGJ-FPLPWBNLSA-N

InChI: InChI=1S/C21H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-20-17-15-18-21(22)19-20/h7-8,15,17-19,22H,2-6,9-14,16H2,1H3/b8-7-

Canonical SMILES: OC1=CC=CC(CCCCCCC/C=C\CCCCCC)=C1

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