[패/곰피/감태/곤포 표준물질][Phenols] Eckol (에콜; 엑콜) [CFN91603][CAS no. 88798-74-7]_Chemfaces - 코아사이언스
Eckol
Cat.# CFN91603 / Size: 5mg
Cas No.: 88798-74-7
Purity: > 98%
C18H12O9 = 372.28
Physical Description: Powder
[ Source ]
The herbs of Ishige okamurae
[ Biological Activity ]
Eckol have anti-inflammatory,anti-tumor and cytoprotective effects. Eckol inhibits ultraviolet B-induced cell damage by a decrease in oxidative stress in human keratinocytes. Eckol shows effective protective activity against TNF-α/IFN-γ-induced skin inflammation.
[Solvent]
hloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
[Storage]
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8°C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
[After receiving]
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
[ References ]
1. Planta . 2015 Jun;241(6):1313-1324. Physiological role of phenolic biostimulants isolated from brown seaweed Ecklonia maxima on plant growth and development[Pubmed: 25672504]
2. Biol Pharm Bull . 2012;35(6):873-880. Eckol inhibits ultraviolet B-induced cell damage in human keratinocytes via a decrease in oxidative stress[Pubmed: 22687478]
3. Int Immunopharmacol . 2020 Feb 20;82:106146. Eckol from Ecklonia cava ameliorates TNF-α/IFN-γ-induced inflammatory responses via regulating MAPKs and NF-κB signaling pathway in HaCaT cells[Pubmed: 32088638]
4. Nutrients . 2020 May 9;12(5):1361. Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice[Pubmed: 32397556]
5. Phytother Res . 2008 Feb;22(2):238-242. Protective effect of phlorotannin components phloroglucinol and eckol on radiation-induced intestinal injury in mice[Pubmed: 17886227]
6. Bioorg Med Chem Lett . 2012 Jun 1;22(11):3710-3712. Vascular barrier protective effects of eckol and its derivatives[Pubmed: 22543027]
7. Nutrients . 2020 May 9;12(5):1361. Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice[Pubmed: 32397556]
8. Exp Ther Med . 2019 Oct;18(4):2825-2832. Eckol inhibits Reg3A-induced proliferation of human SW1990 pancreatic cancer cells[Pubmed: 31572529]
9. Int J Mol Sci . 2020 Jul 3;21(13):4755. Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF[Pubmed: 32635412]
관련 상품
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