phyproof® Regulation on Cosmetic Products_PhytoLab - 코아사이언스
phyproof® Regulation on Cosmetic Products
Whether for quality control or research: PhytoLab is offering you an outstanding portfolio of highly purified phyproof® reference standards for your analysis and development of cosmetic products which must undergo a safety assessment before they are placed on the market.
The safety assessment includes an evaluation of all ingredients for substances restricted or prohibited by Commission Regulation (EU) 2024/996 amending Regulation (EC) No. 1223/2009 on cosmetic products.[1] These substances have allergenic properties or may pose a risk to human and animal health. Certain fragrance compounds may have allergenic properties and must be indicated on the container and packaging. The list of allergenic fragrances (Annex III) includes numerous ingredients of essential oils as well as many essential oils themselves, e.g., trans-Anethole, β-Caryophyllene, (-)-Menthol, α-Pinene, β-Pinene or α-Terpineol, as well as ylang-ylang, cinnamon oils, citrus oils, or peppermint oils.[2,3]
Only recently, naturally occurring compounds with endocrine disruptor properties have been subject to scientific and regulatory scrutiny. The Scientific Committee on Consumer Safety (SCCS) has evaluated Resorcinol, and the isoflavones Daidzein & Genistein, constituents of soya or red clover extracts, for use in natural cosmetic products. Their maximum concentration in the ready to use preparation is specified in Annex III of Regulation (EC) No 1223/2009 with 0.007 % for Genistein and 0.02 % for Daidzein. From November 1, 2025, products containing Daidzein & Genistein have to meet these provisions.
Furthermore, p-Cymene occurring, e.g., in rosemary oil or tea tree oil is under scrutiny by European authorities and will possibly be classified as CMR Cat. 1b. We will keep you informed about the outcome and consequences.
Our fully documented high purity phyproof® reference standards of relevant substances for regulation on cosmetic products meet all the requirements for your quality control or research projects.
Find your compound below:
| Name | CAS # |
| Aconitine | 302-27-2 |
| Alizarin | 72-48-0 |
| Anthraquinone | 84-65-1 |
| trans-Anethole | 4180-23-8 |
| Aristolochic acid I | 313-67-7 |
| Aristolochic acid II | 475-80-9 |
| Benzyl alcohol | 484-20-8 |
| Brucine | 357-57-3 |
| DL-Camphor | 76-22-2 |
| Cantharidin | 56-25-7 |
| (-)-Carvone | 6485-40-1 |
| (+)-Carvone | 2244-16-8 |
| Catechol | 120-80-9 |
| β-Caryophyllene | 87-44-5 |
| Citral | 5392-40-5 |
| Colchicine | 64-86-8 |
| Convallatoxin | 508-75-8 |
| p-Cymene | 99-87-6 |
| Daidzein | 486-66-8 |
| Esculentoside A | 65497-07-6 |
| Genistein | 446-72-0 |
| Hydrastine | 118-08-1 |
| Hydroquinone | 123-31-9 |
| Imperatorin | 482-44-0 |
| Linalyl acetate | 115-95-7 |
| (-)-Menthol | 2216-51-5 |
| 7-Methoxycoumarin | 531-59-9 |
| Methyl salicylate | 119-36-8 |
| Oleandrin | 465-16-7 |
| α-Pinene | 80-56-8 |
| β-Pinene | 127-91-3 |
| Pyrogallol | 87-66-1 |
| Resorcinol | 108-46-3 |
| Sesamol | 533-31-3 |
| Strychnine | 57-24-9 |
| α-Santonin | 481-06-1 |
| α-Terpineol | 98-55-5 |
| Theophylline | 58-55-9 |
| Trioxsalen | 3902-71-4 |
| Vanillin | 121-33-5 |
| Xanthotoxin | 298-81-7 |
[1] https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32024R0996
[2] https://eur-lex.europa.eu/legal-content/DE/TXT/PDF/?uri=CELEX:32023R1545
[3] https://eur-lex.europa.eu/legal-content/DE/TXT/PDF/?uri=CELEX:02009R1223-20240404
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Our product range comprises more than 1,500 comprehensively documented phytochemicals
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코아사이언스 coresciences PhytoLab GmbH & Co. KG 독일 한국 대리점 korea biochemical high quality phytochemicals reference standards analytical standard natural active ingredients products 표준품 기능성분 표준물질 지표성분 주성분 유효성분 순품 한방 한약 생약 천연물 신약 식물 유래 천연화합물 천연물