Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Rabbit Monoclonal Antibody [AMRe01542]_EnkiLife - 코아사이언스
Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Rabbit Monoclonal Antibody
Cat. # AMRe01542 / Size: 50ul, 100ul, 500ul
Category: Phospho Antibody
Tags: Human, WB, Unconjugated, Rabbit, Cancer
Summary
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Production Name
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Phosoho-ErbB 2/EGFR (Tyr1248/Tyr1173) Rabbit Monoclonal Antibody
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Description
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Recombinant Rabbit Monoclonal antibody
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Host
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Rabbit
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Application
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WB
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Reactivity
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Human
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Performance
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Conjugation
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Unconjugated
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Modification
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Phosphorylated
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Isotype
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IgG
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Clonality
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Monoclonal Antibody
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Form
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Liquid
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Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Buffer
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Purification
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Affinity Purified
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Immunogen
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Gene Name
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ERBB2
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Alternative Names
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ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340
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Gene ID
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2064
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SwissProt ID
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P04626
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Application
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Dilution Ratio
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WB: 1/500-1/1000
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Molecular Weight
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Calculated MW: 138 kDa; Observed MW: 180 kDa
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Background
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.
Research Area
Cancer
* 본 상품은 오직 연구용으로만 사용 가능합니다. 인체 및 제품화에 사용하실 수 없습니다.
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