Z-YVAD-FMK [TP1466][CAS no. 210344-97-1]_TargetMol - 코아사이언스

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Z-YVAD-FMK

Cat.# TP1466 / Size: 1mg, 2mg, 5mg, 10mg, 50mg, 1 mL * 10 mM (in DMSO)

 

Biological Description

Description	AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.
In vitro	Z-YVAD-FMK (100 μM; 24 hours) significantly mitigated butyrate-induced growth inhibition in Caco-2 cells.

Chemical Properties

Molecular Weight	630.66
Formula	C31H39FN4O9
Cas No.	210344-97-1

Storage & Solubility

Storage	keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information	DMSO: 250 mg/mL (396.41 mM), Sonication is recommended.

References

1.Li H1,et al.Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.J Immunol. 2007 Apr 15;178(8):5271-6.

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Citations

1.Meng Z, Liu H, Zhang J, et al. Sesamin promotes apoptosis and pyroptosis via autophagy to enhance antitumour effects on murine T-cell lymphoma. Journal of Pharmacological Sciences. 2021

 

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