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NOTEXIN (노텍신); Basic phospholipase A2 notexin, svPLA2 [L8104][CAS no. 37223-96-4]_Latoxan 수입/공급 전문 코아사이언스
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2024. 6. 14. 09:48
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NOTEXIN
=Basic phospholipase A2 notexin, svPLA2
Cat.# L8104 / Size: 100ug, 5 x 100ug
| Product ID | L8104-100UG |
| Name | NOTEXIN |
| Molecular formula | Np Fraction: C591H878N164O175S16 Ns Fraction: C591H878N166O175S16 |
| Description | It is a toxic presynaptic phospholipase A2 (PLA2) with potent myotoxic activity. Contains: - Notexin Np (~60%) - Notechis Ns (33%), a minor natural variant with K replaced by R in 16 119-amino acid protein with 7 disulfite bonds , from Notechis scutatus snake venom. |
| Biological activity | Notexin exerts both presynaptic (blocks the release of acetylcholine) and myotoxic activities. |
Chemical and Physical Properties
| Product code | L8104-100UG | Molecular weight | 13574 Da |
| Product name | NOTEXIN | Physical form | |
| CAS No. | 37223-96-4 | Melting point | |
| RTECS | RD3800000 | Solubility | Well in water and saline |
| UNIPROT | P00608;P00609 | Optical Activity | |
| PubChem SID | 134222164 | ||
| PubChem CID | |||
| Purity | > 93 % (HPLC) | ||
| Toxicity(LD50) | IVN-MUS LD50: 25 µg/kg | ||
| Chemical Name | |||
| Storage & Reconstitution Recommandations |
Stable in freeze-dried state. In solution, keep at -20 °C. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use | ||
Bibliographic References
- Karlsson et al. Toxicon (1972). 10:405-413
- Mollier et al. Eur. J. Biochem. (1989). 185:263-270
- Halpert et al., J. Biol. Chem. (1975). 250:6990-6997
- Chwetzoff et al., FEBS Letters (1990). 161(2):226-230
Links
| Product code | L8104-100UG |
| Product name | NOTEXIN |
| External Links | PubMed |
| Biomedical Citations From PubMed | |
| Toxicology Citations From PubMed | |
| PubChem SID | |
| UNIPROT UNIPROT |
* For Pharmaceutical and Medical Research Purposes Only !
코아사이언스 coresciences LATOXAN S.A.S. Latoxan laboratory natural active ingredients France Korea 대리점 venom toxin plant small molecules 연구 목적 독소 식물 유래 저분자 물질 plant substances 카디오독소 심장독소