[사람/인간 핵내수용체/핵 수용체 단클론 항체] Monoclonal Antibodies to 48 Human Nuclear Receptors_Funakoshi - 코아사이언스
Monoclonal Antibodies to 48 Human Nuclear Receptors
Nuclear hormone receptors are a family of 48 intracellular receptors. Lipid-soluble ligand bound receptors
move to the nucleus to function as transcriptional activators, associating with other general transcription factors.
This regulates gene ｅxpression relates to various metabolic pathways.
Malfunctions in nuclear hormone receptor signaling pathways caused by an individuals' habits leads
to a variety of life-style related diseases, such as type II diabetes, obesity, hyperlipidemia, and
circulatory disorders.
Perseus Proteomics Inc.'s mouse monoclonal antibodies have high affinity and specificity for nuclear receptors.
All antibodies are validated by the reactivity with the proteins from full length cDNA expressed in mammalian cells.
Features
・ Raised in Perseus Proteomics Inc.
・ Validated by full length proteins
・ Application : ELISA and Western Blot.
Some antibodies can be used for immunohistochemistry (IHC).
・ Reactivity : Human (Some antibodies crossreact with rat or mouse)
■ Androgen Receptor
#PP-H7507-00 Anti-Androgen Receptor, Human, Mouse-Mono(H7507) <Anti-AR>
Human Prostate Gland (Paraffin Section)
■ Estrogen Receptor
#PP-H4624-00 Anti-Estrogen Receptor α, Human, Mouse-Mono(H4624) <Anti-ERα>
Human Uterus Endometrial Epithelium (Paraffin Section)
#PP-H5844-00 Anti-Estrogen-Related Receptor α, Human, Mouse-Mono(H5844) <Anti-ERRα>
Human Heart Myocardium (Paraffin Section)
Products
| Target | Cat.# | Immunogen | Cross- reactivity |
Application | Size | Storage |
| Androgen Receptor (AR) | PP-H7507-00 | Human | M, R | E, WB, IP, IHC | 100μl | -20℃ |
| Constitutive Androstane Receptor (CAR) | PP-N4111-00 | Human | M, R | E, WB, NW, IP IHC | ||
| Chicken ovalbumin upstream promotor transcription factor 1 (COUP-TFI) | PP-H8132-00 | Human | M, R | E, WB, IP, IHC | ||
| PP-H8124-00 | Human | M, R | E, WB, NW, IHC | |||
| Chicken ovalbumin upstream promoter transcription factor 2 (COUP-TFII) | PP-H7147-00 | Human | M, R | E, WB, IP, IHC | ||
| DSS-AHC critical region on the X chromosome, gene1 (DAX1) | PP-H7431-00 | Human | E, WB | |||
| V-erbA related orphan nuclear receptor (EAR2) | PP-N2025-00 | Human | R | E, WB, NW, IP, IHC | ||
| PP-H9929A-00 | Human | M, R | E, WB, NW, IHC | |||
| Estrogen Receptor alpha (ER alpha) | PP-H4624-00 | Human | M, R | E, WB, IP, IHC | ||
| Estrogen Receptor beta (ER beta) | PP-PPZ0506-00 | Human | E, WB, IP | |||
| Estrogen-Related Receptor alpha (ERR alpha) | PP-H5844-00 | Human | M, R | E, WB, NW, IP, IHC | ||
| Estrogen-Related Receptor beta (ERR beta) | PP-H6705-00 | Human | M, R | E, WB, NW, IP, IHC | ||
| PP-H6707-00 | Human | E, WB, NW, IP | ||||
| Estrogen-Related Receptor gamma(ERR gamma) | PP-H6812-00 | Human | M, R | E, WB, IP IHC | ||
| Farnesoid X-activated receptor (FXR) | PP-A9033A-00 | Human | M, R | E, WB, IP, IHC | ||
| Germ Cell Nuclear Factor (GCNF) | PP-H7921-00 | Human | WB, NW, IP | |||
| Glucocorticoid Receptor, Common (GR) | PP-H8031-00 | Human | M, R | E, WB, IP, IHC | ||
| Glucocorticoid Receptor, Common (GR) | PP-H8004-00 | Human | R | E, WB, IP, IHC | ||
| Hepatocyte nuclear factor 4-alpha (HNF4 alpha) | PP-H1415-00 | Human | M, R | E, WB, NW, S, IP, IHC, ChIP | ||
| PP-K9218-00 | Human | M, R | E, WB, S, IP, IHC | |||
| Hepatocyte nuclear factor 4-alpha (HNF4 alpha7) | PP-H6939-00 | Human | M, R | E, WB, NW, IP IHC | ||
| Hepatocyte nuclear factor 4-gamma (HNF4) | PP-B6502A-00 | Human | R | E, WB, NW, IP IHC | ||
| PP-N3224-00 | Human | M, R | E, WB, NW, IHC | |||
| Liver Receptor Homologue 1 (LRH-1) | PP-H2325-00 | Human | M, R | E, WB, IP | ||
| PP-K8801-00 | Human | E, WB, IP | ||||
| Liver X Receptor alpha (LXR alpha) Ligand Binding Domain | PP-PPZ0412-00 | Human | M, R | E, WB, S, IP, IHC ChIP | ||
| Liver X Receptor alpha (LXR alpha) | PP-K8607-00 | Human | E, WB, S, IP, ChIP | |||
| Liver X Receptor beta (LXR beta) | PP-K8917-00 | Human | E, WB, NW, IP | |||
| Mineralocorticoid Receptor (MR) | PP-H3122-00 | Human | M, R | E, WB, IP, IHC | ||
| Nerve growth factor-induced clone B alpha (NGFI-B alpha) | PP-H1648-00 | Human | E, WB, IP | |||
| Nerve growth factor-induced clone B beta (NGFI-B beta) | PP-N1404-00 | Human | M, R | E, WB, NW, IP, IHC | ||
| Nerve growth factor-induced clone B gamma (NGFI-B gamma) | PP-H7833-00 | Human | E, WB, IP | |||
| Photoreceptor-specific Nuclear Receptor (PNR) | PP-H7223-00 | Human | R | E, WB, IHC | ||
| Peroxisome Proliferator-Activated Receptoralpha (PPAR alpha) | PP-H0723-00 | Human | M | E, WB, S, IP, ChIP | ||
| Peroxisome Proliferator-Activated Receptor gamma (PPAR gamma, Common) | PP-A3409A-00 | Human | M, R | E, WB, S, IP, IHC, ChIP | ||
| PP-K8713-00 | Human | M | E, WB, S, IP, ChIP | |||
| Peroxisome Proliferator-Activated Receptor gamma2 (PPAR gamma2) | PP-K8450B-00 | Human | M | E, WB, NW, S | ||
| Peroxisome Proliferator-Activated Receptor delta (PPAR delta) | PP-K9436-00 | Human | E, WB, S | |||
| Progesterone Receptor, Common (PR) | PP-A9621A-00 | Human | M, R | E, WB, NW, IP, IHC | ||
| Progesterone Receptor, Isoform B (PR) | PP-H5344-00 | Human | M, R | E, WB, NW, IP, IHC | ||
| Pregnane X receptor (PXR, Common) | PP-H4417-00 | Human | E, WB, NW, IP | |||
| Pregnane X receptor (PXR-2) | PP-H0502-00 | Human | E, WB, NW | |||
| Pregnane X receptor alpha (RAR alpha) | PP-H1920-00 | Human | E, WB, NW, IP | |||
| Pregnane X receptor beta (RAR beta) | PP-H4338-00 | Human | E, WB, IP | |||
| Pregnane X receptor gamma (RAR gamma) | PP-H5620-00 | Human | E, WB, IP | |||
| Rev-erb alpha (REVERB alpha) | PP-A8740A-00 | Human | E, WB, NW, IP | |||
| Rev-erb alpha (REVERB beta) | PP-H2729-00 | Human | R | E, WB, IP, IHC | ||
| RAR-related orphan receptor (ROR), Common | PP-H3925-00 | Human | M, R | E, WB, IP IHC | ||
| RAR-related orphan receptor alpha (ROR alpha) | PP-H3910-00 | Human | E, WB, IP | |||
| RAR-related orphan receptor beta (ROR beta) | PP-N7927-00 | Human | E, WB, NW | |||
| RAR-related orphan receptor gamma (ROR gamma) | PP-H6437-00 | Human | E, WB, IP | |||
| Retinoid X Receptor alpha (RXR alpha) | PP-K8508-00 | Human | M, R | E, WB, S, IP, IHC, ChIP | ||
| Retinoid X Receptor beta (RXR beta) | PP-H7341-00 | Human | R | E, WB, NW, IP | ||
| Retinoid X Receptor gamma (RXR gamma) | PP-H3210-00 | Human | E, WB, NW, IP | |||
| Small heterodimer partner (SHP) | PP-N7519-00 | Human | E, WB, NW | |||
| Steroidogenic Factor 1 (SF-1) | PP-N1665-00 | Human | M, R | E, WB, NW, IP, IHC | ||
| Tailless homologue (TLX) | PP-H6506-00 | Human | E, WB, IP | |||
| PP-H6510-00 | Human | M, R | E, WB, IP, IHC | |||
| Tasticular receptor 2 (TR2) | PP-H0037-00 | Human | E, WB, IP | |||
| Tasticular receptor 4 (TR4) | PP-H0107B-00 | Human | M, R | E, WB, IP, IHC | ||
| Thyroid Hormone Receptor alpha (TR alpha) | PP-H2804-00 | Human | M, R | E, WB, NW, IHC | ||
| Thyroid Hormone Receptor beta1 (TR beta1) | PP-H3825A-00 | Human | E, WB, IP | |||
| Vitamin D Receptor (VDR) | PP-H4537-00 | Human | M, R | E, WB, IP, IHC |
* Cross-reactivity ; M = Mouse, R = Rat
* Applications ;
E: ELISA , WB: Western Blotting, NW: Non-Reducing Western Blotting, S: Super Shift Assay,
IP: Immunoprecipitaion, IHC: Immunohistochemistory, ChIP: Chromatin Immunoprecipitation
* NOTICE : FOR RESEARCH USE onLY. NOT FOR DIAGNOSTIC USE.
